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Are There Any Antiinflammotroy Medications For Helping A Person With Sanflippo Syndrome MPS III?
I have a nephew that has Sanflippo Sydrome MPS III.....we are currently dealing with joint issues and the inability to be more mobile....Are there any antiimflammatory meds that could possibly help him? We know he is terminal....just trying to keep him as mobile and out of pain as possible.
Wed, 25 Sep 2019
Hello,
ERT-Enzyme replacement therapy (elosulfase alfa) has been shown to improve ambulatory mobility and decrease pain in other related Mucopolysaccharidosis (MPS type IV) but ERT has not been shown to be effective in MPS III.
Both non-opioid and opioid drugs are currently used for pain control. Paracetamol for mild pain, Ibuprofen,Naproxene,Piroxicam for moderate pain has been used.
NSAIDs need after food administration to reduce GI side effects. Antacids are often prescribed with NSAIDs.
Paracetamol is generally free of adverse effects when administered in appropriate therapeutic doses and is most commonly used.
Hope I have answered your query. Let me know if I can assist you further.
Take care
Regards,
Dr Tushar Kanti Biswas, Internal Medicine Specialis
ERT-Enzyme replacement therapy (elosulfase alfa) has been shown to improve ambulatory mobility and decrease pain in other related Mucopolysaccharidosis (MPS type IV) but ERT has not been shown to be effective in MPS III.
Both non-opioid and opioid drugs are currently used for pain control. Paracetamol for mild pain, Ibuprofen,Naproxene,Piroxicam for moderate pain has been used.
NSAIDs need after food administration to reduce GI side effects. Antacids are often prescribed with NSAIDs.
Paracetamol is generally free of adverse effects when administered in appropriate therapeutic doses and is most commonly used.
Hope I have answered your query. Let me know if I can assist you further.
Take care
Regards,
Dr Tushar Kanti Biswas, Internal Medicine Specialis
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