Hi, thanks for writing to HCM. There is no direct correlation between anemia and muscle twitches. Muscle twitches are caused by our muscles tightening up ( contracting ) involuntarily — in other words, when we re not actually controlling them. Muscle twitches can happen for lots of reasons, like stress, too much caffeine, a poor diet, exercise, or as a side effect of some medications. Although most twitches go away in a few days and are nothing to worry about, some twitches can be caused by nerve problems or other medical conditions. Let your doctor know if: • you have a twitch that doesn t go away • you notice weakness, tingling, or numbness in the area where you get muscle twitches • it looks like the muscle is getting smaller Getting enough sleep, avoiding too much caffeine, and eating healthy foods (like lots of fruits and vegetables), can help prevent some muscle twitches. If your symptoms are not resolving with the above measures, consult a Neurophysician for further workup and management. Hope this information is helpful. Good day