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Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Are Mefloquine and USP advisable for malaria?

I was given four pills..white with #54 and 111 on one side and was given four pills sealed in silver with mefloquine HCl tablet USP 250 mg to treat or prevent malaria since I will be traveling to Africa soon. Are the pills the same and are their safer drugs I can take? Thanks for your help.
Wed, 21 Mar 2018
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General & Family Physician 's  Response

Yes, either of these pills is advisable for malaria. The white pills bearing an imprint of "54 111" on one side and a dividing line on the other side contains the antimalarial drug Mefloquine which is same as that of Mefloquine HCl USP. It can be used to treat or prevent malaria.

Since you're planning to travel to Africa, should take one dose of Mefloquine per week starting at least two weeks before traveling to Africa. Then you should continue taking one dose per week while there, and for four consecutive weeks after leaving.

Generally, it is well-tolerated, however, it can cause dizziness, difficulty sleeping, anxiety, vivid dreams, and visual disturbances. In rare instances, it can cause seizures, depression, and psychosis. When they occur, these side effects start within the first few doses of the medicine.

Hope I have answered your query. Let me know if I can assist you further.

Dr. Mohammed Taher Ali
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