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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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25 Year Old Diagnosed With Stage 5 IgA Necropathy. Have Kidney Stones. Elevated Creatinine Levels And High Protein. Coulds This Be Reversed?

My son, age 25, was, in the past week, diagnosed with stage 5 Iga Necropathy. At first, since the onset was so sudden, they thought it was acute but upon performing a kidney biopsy , showed that the left kidney was atrophied. His creatinine levels were elevated to 800 and high protein . Can it be possible that while one kidney is atrophied that the other kidney have only temporary damage and can be reversed?
Thu, 6 Sep 2012
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General & Family Physician 's  Response
Hi, I am so sorry to hear that your son is unwell

IgA nephropathy is a type of inflammatory disease of the glomeruli (parts of the kidneys).The inflammation of the glomeruli is called glomerulonephritis and IgA is the most common type in the world. IgA nephropathy is characterised by deposition of IgA antibodies (antibodies are normallly used by your body to fight infection and disease).
The disease is highly variable and can range from no symptoms to rapidy progressing.
The treatment involves monitoring your son's urine for protein or blood, blood pressure control to prevent the blood pressure from causing further damage (some blood pressure medications would also reduce the proteins in the urine, steroid use,low protein diet.
Poor Prognosis is usually determined by: persistant hematuria (blood in the urine), persistant proteinuria, sustained high blood pressure, impaired renal function,smoking. Some histological findings (what is seen in biopsy) can also affect outcome.

It is unlikely to affect the kidneys differently.

I hope that your son improves
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25 Year Old Diagnosed With Stage 5 IgA Necropathy. Have Kidney Stones. Elevated Creatinine Levels And High Protein. Coulds This Be Reversed?

Hi, I am so sorry to hear that your son is unwell IgA nephropathy is a type of inflammatory disease of the glomeruli (parts of the kidneys).The inflammation of the glomeruli is called glomerulonephritis and IgA is the most common type in the world. IgA nephropathy is characterised by deposition of IgA antibodies (antibodies are normallly used by your body to fight infection and disease). The disease is highly variable and can range from no symptoms to rapidy progressing. The treatment involves monitoring your son s urine for protein or blood, blood pressure control to prevent the blood pressure from causing further damage (some blood pressure medications would also reduce the proteins in the urine, steroid use,low protein diet. Poor Prognosis is usually determined by: persistant hematuria (blood in the urine), persistant proteinuria, sustained high blood pressure, impaired renal function,smoking. Some histological findings (what is seen in biopsy) can also affect outcome. It is unlikely to affect the kidneys differently. I hope that your son improves