i have been diagnosed with CKD, SLE, and am having
I have gone through your question and I understand your concerns but since you are suffering from CKD and SLE then prednisone is necessary to avoid the adverse effects of systemic lupus on the kidney which might lead to further progression of you renal insufficiency...
However, if the adverse effects are not well tolerated then you can refer to your doctor to decrease the daily dose..
I hope you find this helpful
Feel free to ask further...