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Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

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can I take sildenafil with omeprazole

Answered by
Dr. Vaishalee Punj

General & Family Physician

Practicing since :2003

Answered : 2308 Questions

Posted on Thu, 14 Feb 2019 in Internal Doctor Category
Question: can I take sildenafil with omeprazole
Answered by Dr. Vaishalee Punj 1 hour later
Brief Answer:
Reports of omeprazole to cause erectile dysfunction

Detailed Answer:
Hello and welcome to Ask A Doctor service.

I have reviewed your query and here is my advice.

There are some reports that Omeprazole can cause erectile dysfunction. Also omeprazole inhibits the cytochrome enzymes and sidenafil is metabolized by some of them. So theoretically there maybe accumulation of sildenafil.

But I could not find clinically relevant drug interactions between the two medicines and these can be combined. To be safe, take lower dose of sildenafil.

Dr Vaishalee
Above answer was peer-reviewed by : Dr. Vaishalee Punj

The User accepted the expert's answer

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