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Why are Gabapentin and Ropinirole prescribed for restless leg syndrome?

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Posted on Thu, 17 Jul 2014
Question: Why would my dr. prescribe two meds for restless leg syndrome. Gabapentin 300 MG and Ropinirole 0.5 MG?
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Answered by Dr. Michelle Gibson James (2 hours later)
Brief Answer:
to maximise your relief

Detailed Answer:
HI, thanks for using healthcare magic

These two agents are in different family of drugs and work in different ways.

Ropinirole is what is called a dopaminergic agent and gabapentin is an anticonvulsant (anti seizure medication though used in a lot of other conditions).

It is thought that the dopaminergic agents like ropinirole would improve the sensory symptoms associated with restless leg syndrome. Sensory symptoms would be feelings of abnormal sensations such as nerve pain, tingling etc

Gabapentin helps with both sensory and motor (movement) symptoms.

Your doctor may have suggested the combination so that they could work together to help relieve your symptoms.

There are no known interactions between these agents.

I hope this helps, feel free to ask any other questions
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16811 Questions

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Why are Gabapentin and Ropinirole prescribed for restless leg syndrome?

Brief Answer: to maximise your relief Detailed Answer: HI, thanks for using healthcare magic These two agents are in different family of drugs and work in different ways. Ropinirole is what is called a dopaminergic agent and gabapentin is an anticonvulsant (anti seizure medication though used in a lot of other conditions). It is thought that the dopaminergic agents like ropinirole would improve the sensory symptoms associated with restless leg syndrome. Sensory symptoms would be feelings of abnormal sensations such as nerve pain, tingling etc Gabapentin helps with both sensory and motor (movement) symptoms. Your doctor may have suggested the combination so that they could work together to help relieve your symptoms. There are no known interactions between these agents. I hope this helps, feel free to ask any other questions