When will effect of Cefepime wear off and how to get sleep?

Posted on Mon, 17 Mar 2014

Question: my mom took cefepime and incurred confusion right now and she had dialysis a while ago and did not sleep since last night and we are now 4pm in the philippines,when do you think this drug will wear off and how to do about her sleep. thanks betty

Answered by Dr. Lohit K (45 minutes later)

Brief Answer: more than 10 hours. Detailed Answer: Hi XXXX, thanks for using HCM. I went through the query and understood your concern. Cefepime is a fourth generation cephalosporin with half life of 2 hours in patients with good renal activity. That means it takes 8-10 hours for excretion. It is excreted mainly through kidneys. In renal failure patients the drug action will be prolonged and its excretion depends one the renal activity or dialysis but will be more than 10 hours. More over the drug will be in higher concentration in CSF and hence the time taken for action and elimination from CSF will be more than 10hours. I hope this information helps you. Feel free to ask if any further queries and I will be glad to answer them. Wish you and your family a very happy life and good health. Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar