Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

193 Doctors Online
Doctor Image
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

What treatment should be done for breast lump?

Answered by
Dr.
Dr. Das Arindam

General & Family Physician

Practicing since :2008

Answered : 1416 Questions

default
Posted on Mon, 7 Jan 2013 in Breast Cancer
Question: The breast lump got trucut biopsy and report cance the oncologist has suggested few test like ER,PR,CErbb2 and ki67 and bone scan test ,after that he will start cemotherapy to kill cancer cells , then once lump reduced in size(presently size is approx is 6cm by 8cm) will operate .'other dr. suggest immediate surgery and then cemo.
we are confused what to do.
pl guide.
doctor
Answered by Dr. Das Arindam 1 hour later
Hello,
Thank you for posting a query.

Firstly, you should provide the total impresseion written at the last part of the biopsy report. This is important.

Some points determine need of neoadjuvant (chemotherapy given before surgery) chemotherapy :
1.     Size more than 5 cm. These tumors have higher chance of recurrence.
2.     Tumor differentiation.
3.     ER / PR expression of the tumor cells. In case of tumor containing cells expressing these receptors, the prognosis is excellent. Early starting of the treatment will help the tumor to reduce in size and help the clinician to detect the proper line of treatment depending upon the response of these hormonal agents. This point is not applicable in tumors expressing low ER / PR.
4.     Her2 Neu expression by the tumor cells. In case of positive tumor, chance of recurrence is greater. So, surgical extension and line of treatment can easily be determined by the clinician depending upon the expression of this marker.

So, in your case, lump is larger than 5cm. But, you have to do the tests for ER, PR, and Her2Neu. these are most important. Erbb2 and ki67 are not important in this stage. But as you have to do immunohistochemistry test on the biopsy slide, it is better to do all these at a time.

Lastly, you really need chemotherapy before surgery depending upon the size only. So, it is better to do the tests, mentioned above and go for chemotherapy before surgery.

Hope this information suffices. Let me know, if you have any more question.

Regards.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
premium_optimized

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions ,   ,  
Treatment/Therapy
Medical Topics

Recent questions on  Brain tumor

doctor1 MD

My son Sameer is suffering from foll.symptoms-1.Pulling/twitching sensation on right jaw.2.Headache.3.Vertigo on closing eyes.4.Acidity.We consulted neurologist.After MRI he was referred to ENT surgeon for choked sinuses.ENT surgeon called for CT scan which revealed that there is a small cyst each in maxillary and sphenoid sinuses.We have come to know that complications may arise on surgical treatment due to close proximity of imp.structures to the sphenoid.Is there alternative course of treatment? Kindly advise.

doctor1 MD

my name is lakshmi i had gone through CT scan and MRI scan and they told i have brain tumour and the doctor has given me macbutin before food and forecos kit after food i should continue for 20 days and the tumour will vanish is that true are should go for the opreation.

doctor1 MD

i was diagnosed with a brain tumor, i had 2 brain surgeries, 6 weeks of radiation, and just finished 1 year of chemotherapy. After finishing the radiation treatment, i lost the hair on the front and middle off my head.Its been 15 months since finishing the radaition and the hair that has grown in is very fine and sparse.Do you know how long i will have to wait for it to grow in,it use to be thick and full.

doctor1 MD

I'm trying to ask for my bf who has somes ball shape creamy substance (size is like half a cm sometimes smaller) dropping out from his nose from time to time. He has a benigh brain tumor and wonder if it has anything to do with that. His neurologist can't explain what those are. Please help!

doctor1 MD

Hello I am 65 yr old medical history of osteo arthritis brain tumor removal non cancerous acoustic neuroma which left me deaf in my right ear; during the surgery several nerves were damaged during the surgery resulting a stroke: I have 4 nodules...

doctor1 MD

I had a spinal tap they removed some liquid on 11/22 today is the 11/26 and i still have really bad headaches i cant even get up should i go back to the ER?

doctor1 MD

Hellow sir, I am XXXX XXXXXXX from XXXXXXX XXXXXXX My question is "can brain tumour be transferred through mosquitoes?" My neighbour is suffering from brain tumour and there are so many mosquitoes in my area. So, please tell me that brain tumour...