Question: I have suffered from bipolar depression with manic attacks all of my life, however I didn't learn until about ten years ago that was not problem. I have been on over 10 depression medicines * non of them seemed to help. I am also diagnosed with extreme anxiety disorder, All my life I have slept excessively except when having bipolar maniac attack, and then I would stay up constantly for 3 to 4 days. The doctors have had me on several different medicines. I no longer have the 'ups" associated with manic bipolorism., but have the constant "downs" of biporizm. I am currently taking alprapazon for my "anxiety disorder, Quetiapine 100 MG for Bipolar Disorder, Venlafaxine ER 37.5 MG for depression, & Trintellx 5 Mg. & Montelukast 10 MG. My depression iks so bad a week may go ny without me being able to force myself to get out of bed. It is effecting my health in that I don't eat, have no social life, and is even effecting my personal hygiene. Do you think, these medicine combination should be helping me? I also take 6 other medications at night for medical problem I suffer from & 5 in the morning. I am about at my "?wits" end. This is nol way to live your likfe. Don't worry! I am no suicidal. It goes against my religon