question-icon

What malariaprophylactic medication can be taken with Warfarin?

default
Posted on Wed, 16 Jul 2014
Question: my friend is taking warfarin for his heart condition, and antidepressants and is traveling to Gambia and was wondering which malariaprophylactic medications should he take?
doctor
Answered by Dr. Shoaib Khan (4 hours later)
Brief Answer:
Need to discuss before deciding which med

Detailed Answer:
Hello ma'am and welcome.

Thank you for writing to us.

I have gone through your query with diligence and would like you to know that I am here to help.

Malaria propylaxis includes various drugs, out of which we will have to choose the one most suited for your friend. Assuming your friend is a female, I would like to first clarify whether she is pregnant or is breast feeding, as most medications cannot be used in either of these circumstances. Let me list the medications out for you, and we shall together decide which medication would best suit your friend.

1. Chloroquine:
-Is to be taken once a week
-Best for long trips
-It is a 4 week course
-Course needs to be started 1-2 weeks prior to the travel (if at all your friend is traveling some time in the near future, it is best to avoid this drug)
-Can be used in all stages of pregnancy

2. Doxycycline:
-It is good for a last minute malaria prophylaxis
-Is to be taken on a daily basis
-Added benefit of protection from other infections
-When used in women, can result in vaginal infections
-Is the cheapest out of the lot
-Cannot be used in pregnant and breastfeeding women

3. Atovaquone/Proguanil:
-Cannot be used in pregnant and breastfeeding women
-Is to be taken on a daily basis
-It is expensive
-Best for short trips
-Least side effects out of the lot

4. Mefloquine: (Cannot be used in your friends case)
-Cannot be used in patients with cardiac ailments
-Cannot be used in patients with psychiatric abnormalities

5. Primaquine:
-Best for short trips
-Cannot be used in patients diagnosed or previously not tested to have G6PD (glucose-6-phosphatase-dehydrogenase) deficiency
-Is to be taken on a daily basis
-Cannot be used in pregnant and breastfeeding women
-Can be taken last minute, before travel

As per the above provided list of medications and their features, please let me know which one suits you best, and why. Once we decide which medication is best for you, you can also meet a doctor to get the prescription for the medication.

I hope you find my response both helpful and informative. Please do not hesitate to write back to me for any further clarifications, I would be more than happy to help you.

Best wishes.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Shoaib Khan (10 minutes later)
i think the atokvon/proguanil sounds good....and no need to change his.antidepressants dosage?
doctor
Answered by Dr. Shoaib Khan (8 minutes later)
Brief Answer:
No other changes required

Detailed Answer:
Hello once again.

The patient is male then. And no need to change the dosage of any other medications been taken, continue same ma'am. Please consult a doctor for the prescription, I hope this helps.

Please do not hesitate to write back to me for any further help. I am always available to help.

Best wishes.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Shoaib Khan

General & Family Physician

Practicing since :2009

Answered : 9409 Questions

premium_optimized

The User accepted the expert's answer

Share on
What malariaprophylactic medication can be taken with Warfarin?

Brief Answer: Need to discuss before deciding which med Detailed Answer: Hello ma'am and welcome. Thank you for writing to us. I have gone through your query with diligence and would like you to know that I am here to help. Malaria propylaxis includes various drugs, out of which we will have to choose the one most suited for your friend. Assuming your friend is a female, I would like to first clarify whether she is pregnant or is breast feeding, as most medications cannot be used in either of these circumstances. Let me list the medications out for you, and we shall together decide which medication would best suit your friend. 1. Chloroquine: -Is to be taken once a week -Best for long trips -It is a 4 week course -Course needs to be started 1-2 weeks prior to the travel (if at all your friend is traveling some time in the near future, it is best to avoid this drug) -Can be used in all stages of pregnancy 2. Doxycycline: -It is good for a last minute malaria prophylaxis -Is to be taken on a daily basis -Added benefit of protection from other infections -When used in women, can result in vaginal infections -Is the cheapest out of the lot -Cannot be used in pregnant and breastfeeding women 3. Atovaquone/Proguanil: -Cannot be used in pregnant and breastfeeding women -Is to be taken on a daily basis -It is expensive -Best for short trips -Least side effects out of the lot 4. Mefloquine: (Cannot be used in your friends case) -Cannot be used in patients with cardiac ailments -Cannot be used in patients with psychiatric abnormalities 5. Primaquine: -Best for short trips -Cannot be used in patients diagnosed or previously not tested to have G6PD (glucose-6-phosphatase-dehydrogenase) deficiency -Is to be taken on a daily basis -Cannot be used in pregnant and breastfeeding women -Can be taken last minute, before travel As per the above provided list of medications and their features, please let me know which one suits you best, and why. Once we decide which medication is best for you, you can also meet a doctor to get the prescription for the medication. I hope you find my response both helpful and informative. Please do not hesitate to write back to me for any further clarifications, I would be more than happy to help you. Best wishes.