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What Liver Enzymes Levels Signify Liver Damage?

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Posted on Wed, 29 Jun 2016
Question: What Liver Enzymes levels signify serious liver damage? I am getting a lot of different information.
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Answered by Dr. Michelle Gibson James (1 hour later)
Brief Answer:
imaging is the next normal step

Detailed Answer:
HI, thanks for using healthcare magic

I agree with the church, the numbers are increased but do not warrant a biopsy normally.

An ultrasound to take a non invasive look at the liver can be the next step.

The normal AST and ALt can vary slightly from one lab to the next but in general the upper limit of ast is 40 and the alt 56.
A mild to mod increase would be defined as two to three times the upper limit.

An ultrasound or other non invasive imaging (eg ct) would visualize the liver and would give a possible indication as to the cause.
Most common causes are : (a)infection,
(b) non alcoholic fatty liver- build up of fat in the liver due to diet and inactivity, can lead to inflammation if no changes made
(c)side effect of medication eg statins
(d)trauma
(e)mass in the liver
(f)alcohol

I hope this helps, feel free to ask any other questions
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16808 Questions

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What Liver Enzymes Levels Signify Liver Damage?

Brief Answer: imaging is the next normal step Detailed Answer: HI, thanks for using healthcare magic I agree with the church, the numbers are increased but do not warrant a biopsy normally. An ultrasound to take a non invasive look at the liver can be the next step. The normal AST and ALt can vary slightly from one lab to the next but in general the upper limit of ast is 40 and the alt 56. A mild to mod increase would be defined as two to three times the upper limit. An ultrasound or other non invasive imaging (eg ct) would visualize the liver and would give a possible indication as to the cause. Most common causes are : (a)infection, (b) non alcoholic fatty liver- build up of fat in the liver due to diet and inactivity, can lead to inflammation if no changes made (c)side effect of medication eg statins (d)trauma (e)mass in the liver (f)alcohol I hope this helps, feel free to ask any other questions