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What is the suggested medication for mycobacterium tuberculosis in endometrial tissue?

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Posted on Thu, 20 Feb 2014
Question: hi..detected mycobacterium tb in endometrial tissue..no tb detected in blood samples and no signs of swelling after mantoux test....i am unable to conceive ...is TB the reason for not able to be pregnant and what medications do i need to take?
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Answered by Dr. Aarti Abraham (32 minutes later)
Brief Answer: AKT FOLLOWED BY LAPAROSCOPY SHOULD BE DONE. Detailed Answer: Hello Thanks for writing to us with your health concern. If endometrial biopsy is positive for mycobacterium Tuberculosis, then yes, you are indeed suffering from genital tuberculosis. That could be one reason for inability to conceive. Tuberculosis can affect the lining of the uterus, damaging it, or can cause adhesions that lead to blockage of the fallopian tubes. You should go for AKT ( anti Kochs treatment also called ATT - antitubercular treatment ) . THis is generally prescribed for 6 months duration. After the first two months ( active phase of treatment ) you can start planning for a baby. After the course is completed, you can go for a laparoscopy and hysteroscopy which will show whether the uterus, tubes and ovaries are normal or not. Also, your husband's semen analysis should be done Simultaneously - your hormonal tests should be done, if your cycles are not regular. These include - FSH, LH, TSH, Prolactin, OGTT, Pelvic ultrasound scan and follicular monitoring to track ovulation. Take daily folic acid supplements and maintain an ideal weight. All the best. Please feel free to discuss further.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Aarti Abraham (17 minutes later)
my husband had semen analysis too and his test for TB is negative. is it safe to be sexually active with my husband? my periods are regular. my blood reports have higlighted presence of PDF present. do i have chance of getting pregnant ? and what procedure do i need to follow?
doctor
Answered by Dr. Aarti Abraham (14 hours later)
Brief Answer: DETAILED BELOW Detailed Answer: Hello Yes, it is safe to be sexually active with your husband. You cannot acquire tuberculosis by sexual intercourse. As I said, first start antitubercular treatment. After 2 months of completion of active phase of treatment, you can plan a pregnancy. If you fail to conceive after 3 months of trying, a laparoscopy and hysteroscopy will be needed to answer the question - whether there is any damage to the uterus or tubes. Yes, you definitely have chances of getting pregnant if there is no permanent damage. All the best.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Dr. Aarti Abraham

OBGYN

Practicing since :1998

Answered : 6010 Questions

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What is the suggested medication for mycobacterium tuberculosis in endometrial tissue?

Brief Answer: AKT FOLLOWED BY LAPAROSCOPY SHOULD BE DONE. Detailed Answer: Hello Thanks for writing to us with your health concern. If endometrial biopsy is positive for mycobacterium Tuberculosis, then yes, you are indeed suffering from genital tuberculosis. That could be one reason for inability to conceive. Tuberculosis can affect the lining of the uterus, damaging it, or can cause adhesions that lead to blockage of the fallopian tubes. You should go for AKT ( anti Kochs treatment also called ATT - antitubercular treatment ) . THis is generally prescribed for 6 months duration. After the first two months ( active phase of treatment ) you can start planning for a baby. After the course is completed, you can go for a laparoscopy and hysteroscopy which will show whether the uterus, tubes and ovaries are normal or not. Also, your husband's semen analysis should be done Simultaneously - your hormonal tests should be done, if your cycles are not regular. These include - FSH, LH, TSH, Prolactin, OGTT, Pelvic ultrasound scan and follicular monitoring to track ovulation. Take daily folic acid supplements and maintain an ideal weight. All the best. Please feel free to discuss further.