What does weight gain, tiredness and joints pain after total thyroidectomy indicate?
I have never been a sickly person in my life, just this cancer due (I think) to radiation exposure on the job.
no link I can find between T3 and stroke
Hello Ms. XXXXXXX
I have looked at your labs and your free T3 and free T4 are normal so I can sort of see why your doctor does not want to change your medicine, however I can find no evidence that NDT can cause a stroke in older individuals. In fact I found an article that having a low T3 actually predicts a worse outcome in people who do have a stroke. Here is the reference for that article.
If you are unhappy with your endocrinologist then I suggest that you find another one. Most endocrinologists or primary care doctors are willing to change people to a natural thyroid hormone if they request it. These products are harder to regulate (you have to get more frequent blood tests because the proportion of T3 and T4 is somewhat variable) but I am sure you can find someone to prescribe this if you think it would help you.
I hope you are feeling better very soon,
Thank you so much for replying to my question, and forgive my delay but I couldn't get to my computer until now.
Something I tried to add in my initial question but didn't do it right was, the following:
I too was struck by the full column of "normals" on my test results and couldn't understand it since I am very obviously hypOthyridic. I did actually calculate some ratios which I am led to believe have significance.
My TT4 to TT3 ratio is 74:1 (unless I have made a mistake in the math!) and it is supposed to be 17:1,
My FT3 to rT3 is 15 and it is supposed to be >20
My TT3 to rT3 is 5 while it is supposed to be >10.
It is for these reasons I think I have a conversion (T4 to T3) problem.
Upon reading your reference I am even more determined to fix what I perceive as a T3 conversion problem, do you think that these ratio anomalies are significant?
One final favor, and I hope I am not asking too much. Could you please work out my T4 to T3 ratio and tell me what you get. A 74:1 is absurd but would be a clincher to get transferred to NDT - I do like my Endo and do not want to upset her but I feel she is dead wrong on this one. If I can present her with concrete evidence then I do not feel so bad in requesting a change of doctor.
Thank you so much for your attention, XXXX
free T3 is more important than ratios
Hi again, I think that most endocrinologists feel that free T4 and free T3 are more important than the ratios. When I calculate your total T4 to total T3 ratio
120:8.9 I get 13:1.
I am not sure why you are having such profound symptoms with a normal free T3 and free T4 but I hope you can work things out with our endocrinologist so that you are feeling better.
K. Robinson MD
sorry do not know of a reference
I a sorry but I do not have a reference for this. Usually the ratios are calculated based on the numbers reported to get the ratios without converting them to similar units.
K Robinson, MD
OK all is very clear now, I REALLY appreciate your patience and your explanations, it is really important to me that I understand things. XXXX
P.S. Here is that ref.
HORMONES 2004, 3(2):120-126
The serum triiodothyronine to thyroxine (T3/T4) ratio in various thyroid disorders and after Levothyroxine replacement therapy
A. Mortoglou, H. Candiloros
Department of Endocrinology, Diabetes and Metabolism, XXXXXXX Medical Centre Hospital, XXXXXXX Greece.
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