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What Does Visualized Marrow Signal And Inhomogeneous Distribution Of Red Blood Cells Mean?

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Posted on Fri, 15 Mar 2013
Question: what does visualized marrow signal somewhat inhomogeneous distribution of red blood cells mean on a mri?
doctor
Answered by Dr. Saurabh Gupta (30 minutes later)
Hi,
Thanks for posting your query.

Physiologic demand for more mature blood cells (especially red blood cells) beyond the body's normal capacity to produce them acts to reverse the normal pattern of conversion of red marrow to yellow marrow. This stimulated growth of hematopoietically active marrow increases the visibility of red marrow in the axial and appendicular skeleton. This process is referred to as reconversion or sometimes myeloid hyperplasia. Typically this process occurs in a reverse direction from central to peripheral as demands increase. Examples of this physiologic stress include demands on an endurance athlete, particularly training at high altitude, and cigarette smokers, especially obese women. Other causes include: hyperplastic anemias such as sickle cell disease, thalassemia and spherocytosis.

Hope this will help you. Please do write back if you have any additional concerns.

Wishing you good health...
Regards.
Dr Saurabh Gupta.
Orthopaedic Surgeon.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Saurabh Gupta (16 hours later)
so does that mean i may have leukimia?They said the report said i need clinical test.Does that mean i need a marrow biopsy or what does it mean disease wise?
Those were alotta big words I did not understand.Please tell me in lame mans words so i understand better
doctor
Answered by Dr. Saurabh Gupta (10 hours later)
Hi,
Thanks for posting your query again.

As I have said that there are many condition for inhomogeneous distribution of red blood cells on MRI, you need clinical examination and blood tests.
If your diagnosis can not made after clinical tests and blood test , then you may need marrow biopsy.

Hope this will help you.

Wishing you good health...
Regards.
Dr Saurabh Gupta.
Orthopaedic Surgeon.
Note: For further queries, consult a joint and bone specialist, an Orthopaedic surgeon. Book a Call now.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Saurabh Gupta

Orthopaedic Surgeon, Joint Replacement

Practicing since :2004

Answered : 5930 Questions

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What Does Visualized Marrow Signal And Inhomogeneous Distribution Of Red Blood Cells Mean?

Hi,
Thanks for posting your query.

Physiologic demand for more mature blood cells (especially red blood cells) beyond the body's normal capacity to produce them acts to reverse the normal pattern of conversion of red marrow to yellow marrow. This stimulated growth of hematopoietically active marrow increases the visibility of red marrow in the axial and appendicular skeleton. This process is referred to as reconversion or sometimes myeloid hyperplasia. Typically this process occurs in a reverse direction from central to peripheral as demands increase. Examples of this physiologic stress include demands on an endurance athlete, particularly training at high altitude, and cigarette smokers, especially obese women. Other causes include: hyperplastic anemias such as sickle cell disease, thalassemia and spherocytosis.

Hope this will help you. Please do write back if you have any additional concerns.

Wishing you good health...
Regards.
Dr Saurabh Gupta.
Orthopaedic Surgeon.