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What Does This Endometrial Biopsy Report Indicate?
Question: I am 42 year , since last three months no mmonthly period , when visted doctor , after scanning , they found bulky uterus with Rt cyst 4.1x2.6 cm , now they given cytolog tab for D & C
As prr doctor advice D&C is done and test sample is sent for lab for Endometrial Biopsy and Reault is below.
Gross : Specimen consist of multiple grey brown fragments of tissue amounting to 1.0 cc.
Microscopical features: Sections studied show proliferation of endometrial glands some of them are cystically dilated with papillary infolding . No granulomes or atypical cells seen in sections studied.
IMPRESSION : Simple Hyperplasia with out Ayppia Endometrium.
Please guide what to do next .
As prr doctor advice D&C is done and test sample is sent for lab for Endometrial Biopsy and Reault is below.
Gross : Specimen consist of multiple grey brown fragments of tissue amounting to 1.0 cc.
Microscopical features: Sections studied show proliferation of endometrial glands some of them are cystically dilated with papillary infolding . No granulomes or atypical cells seen in sections studied.
IMPRESSION : Simple Hyperplasia with out Ayppia Endometrium.
Please guide what to do next .
Brief Answer:
you should be placed on cyclical progesterones for next 6 months
Detailed Answer:
Hello,
thanks for the query to hcm,
Th report of endometrial biopsy is simple hyperplasia without atypia simply means that there is no uterine or endometrial cancer but there is progesterone deficiency during the second half of the menstrual cycle which is leading to endometrial hyperplasia under estrogen effect.
So hence you have to be started on TAB MEDROXYPROGESTERONE ACETATE 10mg twice a day from day 15 to day 25 of your cycles for next 6 months to decrease the hyperplasia and initiate regular menses by correcting the hormonal imbalance. After 6 months a repeat endometrial biopsy should be done to reevaluate hyperplasa again.
If not taken then this hyperplasia can lead to irregular shedding and often lead to formation of complex hyperplasia which presents as heavy and irregular bleeding in future.
You may discuss this option with your physician and take an informed decision. Regards
you should be placed on cyclical progesterones for next 6 months
Detailed Answer:
Hello,
thanks for the query to hcm,
Th report of endometrial biopsy is simple hyperplasia without atypia simply means that there is no uterine or endometrial cancer but there is progesterone deficiency during the second half of the menstrual cycle which is leading to endometrial hyperplasia under estrogen effect.
So hence you have to be started on TAB MEDROXYPROGESTERONE ACETATE 10mg twice a day from day 15 to day 25 of your cycles for next 6 months to decrease the hyperplasia and initiate regular menses by correcting the hormonal imbalance. After 6 months a repeat endometrial biopsy should be done to reevaluate hyperplasa again.
If not taken then this hyperplasia can lead to irregular shedding and often lead to formation of complex hyperplasia which presents as heavy and irregular bleeding in future.
You may discuss this option with your physician and take an informed decision. Regards
Note: Revert back with your gynae reports to get a clear medical analysis by our expert Gynecologic Oncologist. Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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