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What Does This Blood Report Indicate?

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Posted on Mon, 20 Jul 2015
Question: The blood test report mentions

Severe anisopoikilocytosis. The RBCs are normo to microcytic / hypochromic with a few elongated cells, teardrop cells, target cells, acanthocytes, spherocytes and schistocytes. No harm parasites on the smear


Please review and suggest the nature of severity

Regards

XXXX
doctor
Answered by Dr. Tushar Kanti Biswas (6 hours later)
Brief Answer:
Blood test reports-interpretation

Detailed Answer:
Hi,

Thank you for your query. I can understand your concerns.
Your blood report apparently shows Microcytic hypochromic anemia indicating iron deficiency anemia.
To know the severity of anemia let me know other blood indices, like HB%,MCV,MCH & MCHC & RDW.
Apart from iron deficiency anemia.
Microcytic hypochromic anemia may also be caused by
Thalassaemia ,Anemia of chronic disease ,Sideroblastic anemia ,Chronic hemolysis ,Haemo-chromatosis,Pregnancy (gender not mentioned).
To differentiate ,you need to undergo tests like Serum iron,TIBC(Total iron binding capacity) & Serum ferritin.
RBCs with anisocytosis (red blood cells of unequal sizes) and poikilocytosis (misshapen red cells ), and target cells are common finding on peripheral blood examination in iron deficiency anemia.
Schistocytes are fragmented RBCs sliced by fibrin bands-e.g. seen in intra-vascular hemolysis.
Acanthocytes/spur cells are RBC showing many irregular spicules
Teardrop cells are seen in thalassaemia .
Spherocytes are small spherical densely stained RBCs with loss of central pallor-found in hereditary spherocytosis, immuno-hemolytic anemias,burns. look for microangiopathic anemia etc.
So one has to interpret peripheral smear report with other indices & serum levels to come to a definitive conclusion.

Regards

Dr. T.K. Biswas M.D. XXXXXXX

Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Tushar Kanti Biswas (12 minutes later)
Sir

Thanks

Attached the blood test reports for your kind review

Fever is coming for more than 15 days and admitted in hospital for last three days

Please suggest
doctor
Answered by Dr. Tushar Kanti Biswas (8 hours later)
Brief Answer:
Complete blood count and peripheral smear reports-interpretation.

Detailed Answer:
Hi,

Thank you for your query. I can understand your concerns.
I have gone through your blood reports and it shows mild iron deficiency anemia.
Toxic changes in neutrophils goes in favor of infection,more precisely bacterial infection,causing fever. Iron deficiency anemia with eosinophilia suggest parasitic infection commonly hookworm infestation causing iron deficiency anemia. Stool test for ova,parasite, cyst and occult blood is indicated. You need further investigation ,presumably for dengue fever as your platelet count is low. However,it is difficult to come to any definite conclusion without detail history and physical examination which is best left to your treating doctors.







Regards

Dr. T.K. Biswas M.D. XXXXXXX

Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Tushar Kanti Biswas (22 hours later)
Sir
Detail blood test reports are attached for further recommendations

Regadrs
XXXX
doctor
Answered by Dr. Tushar Kanti Biswas (4 hours later)
Brief Answer:
Blood report indicating anemia of chronic disease (ACD)

Detailed Answer:
Hi,

Thank you for your query. I can understand your concerns.

All your collective blood report so far shows that you are having mild hypochromic normo-microcytic anemia due to anemia of chronic disease (ACD) which causes disturbed iron metabolism and hypoferremia despite normal body iron stores.

ACD is most often associated with chronic infections, chronic inflammatory diseases ( e.g Connective tissue disorders), Chronic renal failure and neoplastic diseases.

Since your Blood urea ,serum creatinine is normal Chronic renal failure is ruled out. Your Liver function tests are also normal. Hence chronic liver disease can be excluded. Any other underlying chronic inflammation or chronic infection is present to cause abnormal blood report will be best judged by your treating physician and investigated accordingly.

Regards

Dr. T.K. Biswas M.D. XXXXXXX
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
Answered by
Dr.
Dr. Tushar Kanti Biswas

Internal Medicine Specialist

Practicing since :1975

Answered : 1920 Questions

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What Does This Blood Report Indicate?

Brief Answer: Blood test reports-interpretation Detailed Answer: Hi, Thank you for your query. I can understand your concerns. Your blood report apparently shows Microcytic hypochromic anemia indicating iron deficiency anemia. To know the severity of anemia let me know other blood indices, like HB%,MCV,MCH & MCHC & RDW. Apart from iron deficiency anemia. Microcytic hypochromic anemia may also be caused by Thalassaemia ,Anemia of chronic disease ,Sideroblastic anemia ,Chronic hemolysis ,Haemo-chromatosis,Pregnancy (gender not mentioned). To differentiate ,you need to undergo tests like Serum iron,TIBC(Total iron binding capacity) & Serum ferritin. RBCs with anisocytosis (red blood cells of unequal sizes) and poikilocytosis (misshapen red cells ), and target cells are common finding on peripheral blood examination in iron deficiency anemia. Schistocytes are fragmented RBCs sliced by fibrin bands-e.g. seen in intra-vascular hemolysis. Acanthocytes/spur cells are RBC showing many irregular spicules Teardrop cells are seen in thalassaemia . Spherocytes are small spherical densely stained RBCs with loss of central pallor-found in hereditary spherocytosis, immuno-hemolytic anemias,burns. look for microangiopathic anemia etc. So one has to interpret peripheral smear report with other indices & serum levels to come to a definitive conclusion. Regards Dr. T.K. Biswas M.D. XXXXXXX