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What Does This MRI And Bone Scan Indicate?

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Posted on Mon, 17 Nov 2014
Question: I have recently been diagnosed with invasive ductal carcinoma Stage 2. The MRI and Bone Scan show there is no metastasis involvement. The cancer is in just one breast and the lump is 2.5cm x2cmx3.5cm and is ER 2. What does this mean? What would you recommend as the course of treatment? Lumpectomy? Mastectomy Radiation? Chemotherapy? BSO? Tamoxifen ?The MRI also showed that I have a lobulated uterus and fibroids? Is the indicative of a hysterectomy and would you recommend that where I also have breast cancer
doctor
Answered by Dr. Monish De (1 hour later)
Brief Answer:
Hormone receptor positive

Detailed Answer:
Hi

Since you are having invasive ductal carcinoma stage 2 and MRI and bone scan show no metastasis i would recommend mastectomy followed by 6 cycles of chemotherapy to kill the remaining cancer cells followed by radiation and 5 years of tamoxifen therapy.

ER 2 means the cancer is estrogen receptor positive and it has receptors for estrogen.

It suggests that the cancer cells, like normal breast cells, may receive signals from estrogen that could promote their growth.

A the tumour is estrogen receptor positive the cancer will respond to hormonal therapy like tamoxifen.

Hormonal therapy will lower the amount of estrogen in your body and block estrogen from supporting the growth and function of breast cells. If the breast cancer cells have hormone receptors, then these medications could help to slow or even stop their growth.

As you are having having a lobulated uterus and fibroids i would recommend a hysterectomy.

You must also do CT scan of upper abdomen to see whether breast cancer has spread to liver or not

Regards

DR DE

Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Monish De (19 minutes later)
I did have a CT Scan and they said everything was OK. Would you suggest a bilateral mastectomy or unilateral ?
The fibroids are not causing any symptoms but I thought that maybe having a hysterectomy with removal of my ovaries would stop the estrogen. Would this also be helpful for my breast cancer prognosis ? It has been recommended that I have the lumpectomy, chemotherapy for 6 months and radiation with treatment of Tamoxifen, but you would advise a mastectomy. Do you think that this recommnedation is to conservative ?
Thank you
doctor
Answered by Dr. Monish De (12 minutes later)
Brief Answer:
unilateral mastectomy

Detailed Answer:
Hi

I would recommend unilateral mastectomy.

Having hysterectomy with removal of ovaries would stop estrogen and help breast cancer prognosis.

The recommendation is too conservative and i would advise unilateral mastectomy.

If you have no more clarifications then please rate the answer and close the thread.

Regards

DR DE
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Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Monish De

Oncologist

Practicing since :2004

Answered : 2229 Questions

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What Does This MRI And Bone Scan Indicate?

Brief Answer: Hormone receptor positive Detailed Answer: Hi Since you are having invasive ductal carcinoma stage 2 and MRI and bone scan show no metastasis i would recommend mastectomy followed by 6 cycles of chemotherapy to kill the remaining cancer cells followed by radiation and 5 years of tamoxifen therapy. ER 2 means the cancer is estrogen receptor positive and it has receptors for estrogen. It suggests that the cancer cells, like normal breast cells, may receive signals from estrogen that could promote their growth. A the tumour is estrogen receptor positive the cancer will respond to hormonal therapy like tamoxifen. Hormonal therapy will lower the amount of estrogen in your body and block estrogen from supporting the growth and function of breast cells. If the breast cancer cells have hormone receptors, then these medications could help to slow or even stop their growth. As you are having having a lobulated uterus and fibroids i would recommend a hysterectomy. You must also do CT scan of upper abdomen to see whether breast cancer has spread to liver or not Regards DR DE