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What does this IgE level for psoriasis indicate?

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Posted on Wed, 11 May 2016
Question: As part of a screening before taking biological injection for severe placque psoriasis, for the first time in my life I had an allergy test. I am 66 years old.
I did the Ige Total blood test and had a result of 495.3 when normal is supposed to be less than 100.
How should I interpret this and what further allergy tests should I do? I have long suspected possible food allergy to foods I love like choclate or wheat (e.g. in bread).
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Answered by Dr. Michelle Gibson James (1 hour later)
Brief Answer:
may be due to allergies or psoriasis or a combination

Detailed Answer:
HI, thanks for using healthcare magic

There was a medical study conducted in 2010, the summary of which is on medline- titled serum levels of total Ige in patients with psoriasis.

This study found that the levels of IgE were higher in persons with psoriasis. This is one of several studies or articles noting that the level tends to be high.

This may be due to the altered immune response that occurs in psoriasis and there may also be a contribution from any allergies that you may have.

If you wish to determine if allergies are contributing to this high value there are also blood allergy profiles that can be done for foods, drinks, environmental allergens (dust, grass, pollen), chemicals (found in soaps, detergents etc).

Labs have different allergy profiles, one can be chosen that you think covers your possible allergens.
Eg one profile would test for meat/fish only or another for wheat or spice or dust/grass/pollen.
There are a lot.

Your doctor may be able to direct you, should have a list.

I hope this helps , feel free to ask any other questions
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16810 Questions

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What does this IgE level for psoriasis indicate?

Brief Answer: may be due to allergies or psoriasis or a combination Detailed Answer: HI, thanks for using healthcare magic There was a medical study conducted in 2010, the summary of which is on medline- titled serum levels of total Ige in patients with psoriasis. This study found that the levels of IgE were higher in persons with psoriasis. This is one of several studies or articles noting that the level tends to be high. This may be due to the altered immune response that occurs in psoriasis and there may also be a contribution from any allergies that you may have. If you wish to determine if allergies are contributing to this high value there are also blood allergy profiles that can be done for foods, drinks, environmental allergens (dust, grass, pollen), chemicals (found in soaps, detergents etc). Labs have different allergy profiles, one can be chosen that you think covers your possible allergens. Eg one profile would test for meat/fish only or another for wheat or spice or dust/grass/pollen. There are a lot. Your doctor may be able to direct you, should have a list. I hope this helps , feel free to ask any other questions