Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties

190 Doctors Online
Doctor Image
Dr. Andrew Rynne

Family Physician

Exp 50 years

I will be looking into your question and guiding you through the process. Please write your question below.

What does this CT scan regarding diffused large B cell lymphoma indicate?

Answered by
Dr. Monish De


Practicing since :2004

Answered : 1645 Questions

Posted on Wed, 20 Aug 2014 in Blood Disorders
Question: Greetings

I was diagnosed with Diffused Large B Cell Lymphoma in 2013 February. I went through the following treatments:

(1) 6 cycles of CHOP-R and in addition they gave 3 doses of methotroxate chemo (March 2013)

(2) ICE, BEAM followed by Stem Cell Transplant (November 2013)

(3) 20 doses of Radiation. (March 2014)

Latest CT scan report as of XXXXXXX 15 2014 is shown below.

According to my hematologists they have nothing more to do and I have less than one year to live!

I would very much appreciate if anyone could suggest any new drug therapy or alternative therapy that could save my life

-------------------------------------------------------------CT scan report on XXXXXXX 16 2014-----------------------------



Liver: Unremarkable

Gallbladder / ducts: Unremarkable

Pancreas: Unremarkable

GASTROINTESTINAL TRACT: Colonic and duodenal diverticulosis.


Adrenals: Bilateral new adrenal masses as follows:

1. Right, image 22:14 mm

2. Left, image 19:50 mm

Kidneys / Ureters: Bilateral new renal masses as follows:

1. Right, image 34:22 mm

2. Left, image 22:21 mm

Urinary Bladder: Unremarkable

Prostate : Unremarkable


Spleen: Unremarkable

Lymph nodes: Residual but improved lymphadenopathy. Comparison is made

to diagnostic CT from January 8, 2014. The conglomerate retroperitoneal

index node on image 35 measures 30 x 57 mm (prior 52 x 75 mm) V 171" (9 0

PERITONEUM, RETROPERITONEUM & MESENTERY: There is a small amount of free

fluid. There is a new retroperitoneal/perinephric mass, on image 34

measuring 39 mm.

VESSELS & OTHER: Unremarkable

BONES / BODY WALL: Unremarkable


1. Mixed response in the abdomen. There are bilateral new adrenal and renal

masses as well as a new left perinephric mass, most likely progressive

lymphoma. However, the pre-existing retroperitoneal lymphoma demonstrates

some improvement.

2. No convincing thoracic lymphoma. The right upper lobe groundglass

pulmonary nodule is stable compared to the most recent study. Recommend

continued followup.

3. Left thyroid nodule or cyst. Recommend evaluation with ultrasound.
Answered by Dr. Monish De 1 hour later
Brief Answer:
Alisertib, Everolimus

Detailed Answer:

Since you are having bilateral new adrenal and renal masses as well as a new left perinephric mass, suggesting progressive Diffused Large B Cell Lymphoma and you have been treated previously with different chemotherapy regimens some new drugs which are under clinical research like Alisertib, Everolimus and Bortezomib can be tried in your case.

Hope i have answered your query.


Above answer was peer-reviewed by : Dr. Vinay Bhardwaj

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions ,   ,   ,   ,  
Medical Topics ,   ,  

Recent questions on  Pulmonary nodule

doctor1 MD

I just got results from a chest xray: hilar fullness right greater than left, poorly defined possible pulmonary nodule.
The problem is that my pain is on the left side, not relieved by motrin or other nsaids. I also feel a popping at times when I move in certain positions.

doctor1 MD

Yes, I just had a CT scan and it showed that I have a 10 mm Right lung base pulmonary nodule . I am to go back for another CT scan this week of the chest. Does this show that I could have cancer of the lung? Thank you for your answer, Diane McGuffey

doctor1 MD


4 years back incidently doctors found one pulmonary nodule on my right lung on chest X-rays. They asked for CT and the result shown 1.5 cm size. I undergo Bronchoscopy also, but didnt show any problem then. But after these long years I am having on and off fever. Agin asked for Contrast CT. and the result shows that the nodule grew to size of 2.6 cm. and am asked for bronchoscopy again. The first result of bronchoscopy showed on reading like 18HU. is there any possibilty of malignancy. Or is there any risk with that nodule.

doctor1 MD

I Need a Pulmonology Doctor!!! Im driving crazy since I went to the ER and they found in a XRay a Sub-solid nodule 6mm in the lingula ... I repeat another x-ray in 15 days and this is what it says: A nodule is again seen at the left lung base...

doctor1 MD

On 12/31/15 I had an xray of my chest showed a 1.8 Nodule--been there for 5 years. Now it shows a 3.32 X 2.7CM poorly marginated pulmonary lesion in the left perihilary/upper lobe region. No Lymph node involvement yet..HAVE CT SCAN WITH CONTRAST...

doctor1 MD

I am 39 years old and just found out yesterday that a CXR I had last week showed a pulmonary nodule. I am a 3/4 to 1 ppd smoker with a history of persistently elevated WBCs, fibromyalgia, and hypothyroidism. Is it probable that I have an early lung CA? My MGF is deceased from lung CA and PGF deceased from stomach and esophageal CA. Both were smokers. Thank you for your input.

doctor1 MD

3 mm noncalcified pulmonary nodule in the right middle lobe was found on a CTSCAN last month. Wondered if I should be concerned. Just went through removal of right kidney due to Renal Cell Carcinoma. Scheduled for surgery for Hyper-parathyroid May 19, 2014.