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What does the lab test report indicate?

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Posted on Mon, 25 Jul 2016
Question: Dear Doctors
My mothers (age 47) result is
salmn typhi "O" positive dil in 1:80
salmn typhi "H" negative dil in 1.40
salmn P typhi "*A(H)* positive dil in 1.80
salmn P typhi *B(H) positive dil in 1.80

serum creatinine 0.9 mg d/l

please advise
YYYY@YYYY
doctor
Answered by Dr. Panagiotis Zografakis (28 minutes later)
Brief Answer:
probably negative...

Detailed Answer:
Hello,

this test is not the preferred test for Salmonella typhi and paratyphi because it may be negative early or late during the infection and it may be positive even without infection (cross-reactivity with other antigens). Her creatinine is normal or at least not elevated. Interpreting the tests requires knowing the titers of the local population and the symptoms she had. For example if many people in your country have high titers of O and/or H then 1:80 is not high.

Usually 1:80 is not high anyway. O higher than 1:80 (that is 1:160, 1:320 and so on) is required for the diagnosis of acute infection. Does she have symptoms right now? What kind of symptoms? Was she given any treatment? What kind of treatment? Please provide more details and any other test report you may have.

I hope it helps!
Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (10 days later)
Dear Doctor
Thank you for your prompt diagnose and reply

A local doctor in the home town XXXXXXX has prescribed the following

1.Rebeppraole sodium with donperidone (SR) capsule
2.Ferrous ascorbate with folic acid tablet
3.Mltivitamin
4.Vitamin B complex with L-lysine syrup
5.Cholecalcified granules XXXXXXX
6.Antacid suspension
Please advise

Best regards
xxxx
doctor
Answered by Dr. Panagiotis Zografakis (1 hour later)
Brief Answer:
none of them is for Salmonella

Detailed Answer:
You're welcome!

None of the drugs you've mentioned targets Salmonella. The test was no reason to prescribe antibiotics, so I agree with your doctor on not prescribing antibiotics.

Rabeprazole is against stomach acidity. It covers the whole 24 hours. The antacid suspension is a fast but short-lived medication against acidity. Ferrous ascorbate and folic acid provide iron and folic acid (obviously!), both of which are necessary for red blood cell production. The rest are vitamins.

I'm not sure why your doctor prescribed the aforementioned drugs because you haven't told me your symptoms and the reason you asked for medical help, or the rest of the tests you've done so far.

I'll be glad to discuss it further if you'd like to share more information about your case.

Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3801 Questions

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What does the lab test report indicate?

Brief Answer: probably negative... Detailed Answer: Hello, this test is not the preferred test for Salmonella typhi and paratyphi because it may be negative early or late during the infection and it may be positive even without infection (cross-reactivity with other antigens). Her creatinine is normal or at least not elevated. Interpreting the tests requires knowing the titers of the local population and the symptoms she had. For example if many people in your country have high titers of O and/or H then 1:80 is not high. Usually 1:80 is not high anyway. O higher than 1:80 (that is 1:160, 1:320 and so on) is required for the diagnosis of acute infection. Does she have symptoms right now? What kind of symptoms? Was she given any treatment? What kind of treatment? Please provide more details and any other test report you may have. I hope it helps! Kind Regards!