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What Does Non-reactive CMV With High Level Antibodies Indicate?

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Posted on Tue, 8 Apr 2014
Question: What does it mean to have non-reactive CMV with high level antibodies?
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Answered by Dr. Praveen G (55 minutes later)
Brief Answer: It is possible in CMV infection Detailed Answer: Hello, Welcome to Healthcare Magic, Non reactive CMV with high antibody titres is possible in cytomegalovirus infection. To interpret the results, we want which antibody titres is high whether IgG antibodies or IgM antibodies. Presence of only IgM antibodies or IgM antibodies with low avidity IgG antibodies is suggestive of recent infection. Presence of only IgG antibodies indicates recent or latent infection of cytomegalovirus. The best method to confirm whether the patient is having active infection or not is by viral isolation or by molecular method like Polymerase Chain Reactions (PCR). Hope I have answered your query, if you have any further query please feel free to post them. Thank you.
Above answer was peer-reviewed by : Dr. Prasad
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Follow up: Dr. Praveen G (12 hours later)
What is CMV? And what symptoms does it cause?
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Answered by Dr. Praveen G (1 hour later)
Brief Answer: Cytomegalovirus (CMV) Detailed Answer: Hello, It is my pleasure to answer your query, Cytomegalovirus (CMV) is a virus that belongs to herpes group of virus. Cytomegalovirus (CMV) infection can spreads easily through direct contact of body fluids such as saliva,urine,blood,semen,vaginal secretions and breast milk from an infected person. People can also get Cytomegalovirus (CMV) through sexual contact. Most people infected with cytomegalovirus (CMV) do not have any symptoms but acute cytomegalovirus (CMV) infection may cause flu like symptoms such as high grade fever,enlarged lymph nodes, sore throat, muscle aches,loss of appetite and fatigue. Hope you got the answer for your query, if you have any further questions feel free to ask them. Thank you.
Above answer was peer-reviewed by : Dr. Yogesh D
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Answered by
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Dr. Praveen G

Infectious Diseases Specialist

Practicing since :2002

Answered : 2448 Questions

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What Does Non-reactive CMV With High Level Antibodies Indicate?

Brief Answer: It is possible in CMV infection Detailed Answer: Hello, Welcome to Healthcare Magic, Non reactive CMV with high antibody titres is possible in cytomegalovirus infection. To interpret the results, we want which antibody titres is high whether IgG antibodies or IgM antibodies. Presence of only IgM antibodies or IgM antibodies with low avidity IgG antibodies is suggestive of recent infection. Presence of only IgG antibodies indicates recent or latent infection of cytomegalovirus. The best method to confirm whether the patient is having active infection or not is by viral isolation or by molecular method like Polymerase Chain Reactions (PCR). Hope I have answered your query, if you have any further query please feel free to post them. Thank you.