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What Does My Biopsy Report Indicate?

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Posted on Tue, 24 Nov 2015
Question: Show mature lobulated fibroadipose tissue with extensive
organizing fat necrosis, fibrosis, chronic inflammation, and reactive
changes. Prominent perivascular lymphocytosis is also present. What this means?
doctor
Answered by Dr. Mukund Savaskar (37 minutes later)
Brief Answer:
Chronic inflammation with fibrosis of Fatty lesion/ Under Investigation

Detailed Answer:
Brief Ans-Chronic inflammation with fibrosis of Fatty lesion/ Under Investigation

Hi,Thanks for your query in this regard.
I studied your query with a scanty information.
I reviewed your query and found it that it seems to be a Histopath report mostly.

Dear,unless you give more information on the complaints you are having,it is very difficult to reply on this blind query, with scanty information.This is because there are many possibilities to your query and which one is applicable to you,could be replied only after more detailed information.

Hence I would need more details about the disease condition as follows-
What are the complaints you have?
From which site this tissue is studied by Histo-pathology Biopsy?
How long you were suffering from this illness?
What for you did this histopath study?
How did this health issue started with You?

Based on the facts given-It means that -there is chronic inflammatory lesion of the fatty tissue with Vascular chronic inflammation.It could be due to Intra-Muscular Lipoma/Lipo-sarcoma/ Lipo-blastoma and is not predictable and replied.

HenceFor pin pointing on the exact cause of it-I would need more information.
Await your information soon,to be replied in next session.

Welcome for any further query in this regard.

Good Day!!

Dr.Savaskar M.N. XXXXXXX Surgical Specialist
M.S.Genl-CVTS

Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Mukund Savaskar (1 hour later)
Couple of months ago I started to feel a lump in my left groin, I thought that was a hernia, but the doctor wasn't sure, so he decided to do a biopsy. That was 15 days ago (but now I have a biggest lump in that area) what I wrote in the original post was the result of the biopsy. My leg is kind of week and sometimes I limp because my hip kind of hurt. Have a hernia and couple of disk with certain degree of degeneration. I don't know if this is enough. Thanks in advance!
doctor
Answered by Dr. Mukund Savaskar (14 hours later)
Brief Answer:
Lump in Left Groin with Rapid Growth/Under Investigation

Detailed Answer:
Brief Ans-Lump in Left Groin with Rapid Growth/Under Investigation

Clinical and Treatment- Impression-
Possible FibroMyofibroblastoma of the Inguinal Canal with Round Ligamental Lump in left Groin-is the clinical Possibility in your case.
Surgical Excision with Wide Margin Excision -till the final recurrence comes under control is the treatment of this -Locally recurrent Lump in Left Groin.

Hi,Thanks for your query to HCM.
I studied your query regarding the Left Groin Lump,which has grown fast in last 15 days time.

Give following information as follows-
Since how long back you felt a lump in left Groin?
How was that lump-Hard / or soft?With pain on pressure or painless?
What was the size of the lump when it was biopsied 15 days back?
Was it fixed or movable from skin or from the surrounding subcutaneous tissues?
What was the USG / report if done?

My Impression on the Histopath Report-when correlated with the Lump in Left Groin-
i-The lump which was biopsied shows- mature fibrofatty Lobulated tissue-which is suggestive of Benign Fibro-Lipomatous Lump ,due to presence of Mature Fibro-Fatty tissue

ii-with extensive organizing fat necrosis, fibrosis, -Indicating fast Fatty tissue growth causing extensive organising fat necrosis-suggestive of Fast growing Fatty tissue Lump of sarcomatous nature,as there is extensive fat -necrosis with resultant fibrosis.

iii-chronic inflammation, and reactive changes.-These indicate chronic inflammatory reaction which is post-necrosis, resulting ultimately in to Fibrosis.
The reactive changes in the tissue indicates the speedy growth of the chronic inflammatory tissue in this Lump in the left Groin.

iv- Prominent perivascular lymphocytosis-indicating the chronic T cell perivascular aggregation-suggestive of intense T-Cell activity -suggesting fast sarcomatous fatty tissue being attacked as foreign cell mass with resultant extensive fatty necrosis in the given lump in Left Groin.

-Clinico-Pathological Correlation with the Left Groin Lump-
Based on Review of this Histo-path Report and correlating it with a fast grown Lump in just 15 days period

Impression about the Left Groin lump-
This lump which seems to be a FibroFatty fast growing Sarcomatous growth ? MOstly -Lipo-Sarcoma Lump,with extensive fatty necrosis with reactive fibrosis in the lump tissue.
In short it seems to be Locally Malignant / Or and restricted growth with potential to grow / recurr after excision.

LEADS-
Possible FibroMyofibroblastoma of the Inguinal Canal with Round Ligamental Lump in left Groin-is the clinical Possibility in your case.
Surgical Excision with Wide Margin Excision -till the final recurrence comes under control is the treatment of this -Locally recurrent Lump in Left Groin.

Hope this reply would help you to plan further treatment leads with your doctor.
Second Opinion from Surgical Oncologist and from Histopathologist,would give you the exact lead in planning treatment in your unusual case.

Welcome for any further query in this regard,which would be replied in next session.
Await more information about this left Groin Lumps.

Good Day!!

Dr.Savaskar M.N. XXXXXXX Surgical Specialist
M.S.Genl-CVTS
Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
doctor
Answered by
Dr.
Dr. Mukund Savaskar

General Surgeon

Practicing since :1978

Answered : 3606 Questions

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What Does My Biopsy Report Indicate?

Brief Answer: Chronic inflammation with fibrosis of Fatty lesion/ Under Investigation Detailed Answer: Brief Ans-Chronic inflammation with fibrosis of Fatty lesion/ Under Investigation Hi,Thanks for your query in this regard. I studied your query with a scanty information. I reviewed your query and found it that it seems to be a Histopath report mostly. Dear,unless you give more information on the complaints you are having,it is very difficult to reply on this blind query, with scanty information.This is because there are many possibilities to your query and which one is applicable to you,could be replied only after more detailed information. Hence I would need more details about the disease condition as follows- What are the complaints you have? From which site this tissue is studied by Histo-pathology Biopsy? How long you were suffering from this illness? What for you did this histopath study? How did this health issue started with You? Based on the facts given-It means that -there is chronic inflammatory lesion of the fatty tissue with Vascular chronic inflammation.It could be due to Intra-Muscular Lipoma/Lipo-sarcoma/ Lipo-blastoma and is not predictable and replied. HenceFor pin pointing on the exact cause of it-I would need more information. Await your information soon,to be replied in next session. Welcome for any further query in this regard. Good Day!! Dr.Savaskar M.N. XXXXXXX Surgical Specialist M.S.Genl-CVTS