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What does low level of creatinine in urine indicate?

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Posted on Fri, 4 Dec 2015
Question: I have less than 10 mg/l ( .9 mmol/l ) of creatinine in my urine. What does this mean.
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Answered by Dr. Panagiotis Zografakis (47 minutes later)
Brief Answer:
it means nothing...

Detailed Answer:
Hello,

creatinine concentration in the urine means nothing really because it may fluctuate widely depending on the hydration status. Urine creatinine values are commonly used as a way to compare other solutes values taking into account the rate of excretion (represented by creatinine concentration). It can also be used to calculate the glomerular filtration rate (GFR).

I hope you find my comments helpful!
You can contact me again, if you'd like any clarification or further information.

Kind Regards!



Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Panagiotis Zografakis (17 minutes later)
I was under the impression a low urine creatinine meant your kidneys weren't working probably. Can the egfr be measured by urine?
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Answered by Dr. Panagiotis Zografakis (5 minutes later)
Brief Answer:
No and Yes

Detailed Answer:
A spot urine creatinine measurement alone is useless. You can't use it to draw any conclusion at all!
The eGFR (estimated GFR) calculation involves serum creatinine, age, body weight values. The GFR can be calculated by a combination of blood and 24-hour urine collection values. The GFR is more accurate than eGFR.

Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3768 Questions

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What does low level of creatinine in urine indicate?

Brief Answer: it means nothing... Detailed Answer: Hello, creatinine concentration in the urine means nothing really because it may fluctuate widely depending on the hydration status. Urine creatinine values are commonly used as a way to compare other solutes values taking into account the rate of excretion (represented by creatinine concentration). It can also be used to calculate the glomerular filtration rate (GFR). I hope you find my comments helpful! You can contact me again, if you'd like any clarification or further information. Kind Regards!