question-icon

What does an SGPT value of 133 and alkaline phosphate of 103 indicate?

default
Posted on Sat, 25 Nov 2017
Question: My Little brother's SGPT value is 133, Alkaline Phosphatase is 103 and GGT is 65. He is in his 20s. Can someone interpret this for us until we get him to see a doctor tomorrow? Thank you.
doctor
Answered by Dr. Ramesh Kumar (35 minutes later)
Brief Answer:
Patient should be evaluated thoroughly.More then 3 times normal elevation of liver enzymes is significant.

Detailed Answer:
Hello,
Thanks for choosing HealthcareMagic for your query,
Have seen your details and i appreciate your concerns.

The normal range of values for SGOT is about 5 to 40 units per liter of serum (the liquid part of the blood). The normal range of values for SGPT is about 7 to 56 units per liter of serum.Both these enzymes are elevated in your brothers case.As your brother is young and asymptomatic you have not mentioned his symptoms)he should be evaluated for Autoimmune hepatitis (liver inflammation caused by an autoimmune disorder).If his bilirubin levels are also elevated then it could be viral hepatitis also.

Please mention his direct indirect and total bilirubin levels?
Why was his liver function test done? I mean was he symptomatic?If yes what are his symptoms?
Any history of previous illness,medications etc?
These basic details are required before giving any further professional advice.

Waiting for reply.
Thanks.


Above answer was peer-reviewed by : Dr. Prasad
doctor
default
Follow up: Dr. Ramesh Kumar (42 minutes later)
Dr. XXXXXXX

Thank you for answering. His direct Bilirubin is 0.2 and indirect is 0.4, total is 0.6.
He was feeling very weak, and couldn't breath sometimes. Randomly he would fall down. He also complained about his tongue being very salty, with white bumps on it. Primary care physician recommended a glucose test and his sugar levels were extremely below normal range. His blood sugar coefficient was 0.5. Then they recommended a full liver function test. He hasn't had any major illness in a long time. He also mentioned his left hand and foot were numb and Dr gave him a Vit D injection as his Vit D was also low, and that seemed to have helped him. He also has dry throat and cough sometimes.
doctor
Answered by Dr. Ramesh Kumar (11 hours later)
Brief Answer:
Follow up.

Detailed Answer:
Hello again my dear,
After going through your narration i would say that a detailed investigation of hepatobiliary system is required in his case.
20 years is too young a age to suffer from the symptoms he is having.

Panel investigations required are-
CT chest and abdomen with contrast.
2d echo of heart.
Liver function tests.
If possible Fibroscan of liver.
Fasting and PP blood sugar.
Glucose tolerance test.
Serum vitamin B12 levels-Tungling and numbness.
Stool culture and microscopy-Apthous ulcers in mouth can be due to depleted gut flora.
Serum insulin levels- to ruke out cause of blood sugar variation.
Detailed investigations are required as he is symptomatic.
Please discuss this answer with your primary consultant and get these investigations done.

Follow up with reports.
Regards!
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
Answered by
Dr.
Dr. Ramesh Kumar

Gastroenterologist

Practicing since :1986

Answered : 2497 Questions

premium_optimized

The User accepted the expert's answer

Share on
What does an SGPT value of 133 and alkaline phosphate of 103 indicate?

Brief Answer: Patient should be evaluated thoroughly.More then 3 times normal elevation of liver enzymes is significant. Detailed Answer: Hello, Thanks for choosing HealthcareMagic for your query, Have seen your details and i appreciate your concerns. The normal range of values for SGOT is about 5 to 40 units per liter of serum (the liquid part of the blood). The normal range of values for SGPT is about 7 to 56 units per liter of serum.Both these enzymes are elevated in your brothers case.As your brother is young and asymptomatic you have not mentioned his symptoms)he should be evaluated for Autoimmune hepatitis (liver inflammation caused by an autoimmune disorder).If his bilirubin levels are also elevated then it could be viral hepatitis also. Please mention his direct indirect and total bilirubin levels? Why was his liver function test done? I mean was he symptomatic?If yes what are his symptoms? Any history of previous illness,medications etc? These basic details are required before giving any further professional advice. Waiting for reply. Thanks.