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What does a high C reactive protein mean?

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Posted on Wed, 23 Aug 2017
Question: My Son XXXXXXX XXXXXXX was suffering with high fever 104-105 C. We got him admitted in a hospital and following tests were done - CRP, CUE, Dengue, Thyphoid, Malaria. All tests were normal except CRP. It was 51, where as normal range is below 3. He was under observation for 4 days and was given Montaz 500mg and Amikacin 100mg for 5 days. CRP test is repeated on Day5 and now it is 37.7. Doctor is suggesting to continue the same medication for 3 more days and repeat the test. I want second opinion.
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Answered by Dr. Pradeep Kumar Jain (54 minutes later)
Brief Answer:
I agree with your doctor

Detailed Answer:
Hello

Thanks for asking on this platform

I have gone through the query and do understand your concern.
CRP is a marker of bacterial infection and it gives a good clue about the response of treatment.
I would have done the same as your doctor in the given condition.The only thing I would have done extra is blood culture to find out the organism (bacteria) which has caused this infection.
Montaz and Amikacin combination is a very good choice of antibiotic for initial treatment and as the CRP has decreased it suggests that it is working fine. I would like to know about the general well being of the child and about the fever severity. If child is doing well and fever has subsided there is no need to worry much.
Please get a repeat CRP test done after 3 days to check whether it has come down to the normal level. In most of the cases CRP usually gets normal within 7-10 days after proper treatment if infection is not severe.
If repeat CRP is normal, antibiotic can be stopped.


I hope this helps.
Please let me know if you have any more questions.
Wishing for your child's rapid recovery.
Regards

Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Pradeep Kumar Jain

Pediatrician, Cardiology

Practicing since :2006

Answered : 2069 Questions

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What does a high C reactive protein mean?

Brief Answer: I agree with your doctor Detailed Answer: Hello Thanks for asking on this platform I have gone through the query and do understand your concern. CRP is a marker of bacterial infection and it gives a good clue about the response of treatment. I would have done the same as your doctor in the given condition.The only thing I would have done extra is blood culture to find out the organism (bacteria) which has caused this infection. Montaz and Amikacin combination is a very good choice of antibiotic for initial treatment and as the CRP has decreased it suggests that it is working fine. I would like to know about the general well being of the child and about the fever severity. If child is doing well and fever has subsided there is no need to worry much. Please get a repeat CRP test done after 3 days to check whether it has come down to the normal level. In most of the cases CRP usually gets normal within 7-10 days after proper treatment if infection is not severe. If repeat CRP is normal, antibiotic can be stopped. I hope this helps. Please let me know if you have any more questions. Wishing for your child's rapid recovery. Regards