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What does a germinal center positive for Bcl-6 and negative for Bcl-2 indicate?

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Posted on Mon, 6 Aug 2018
Question: What is significance of germinal center positive for Bcl-6 and negative for Bcl-2? Patient has enlarged lymph glands on neck, and necrotic tissue on back of tongue
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Answered by Dr. Dr. Esmeralda Sera (29 minutes later)
Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

Brief Answer:
BCL

There genes are expressed in Non Hodgkin Lemphoma

They have significant in prognosis and therapy of the disease

Hope I have answered your query. Let me know if I can assist you further.
Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Dr. Esmeralda Sera

Oncologist

Practicing since :1998

Answered : 1351 Questions

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What does a germinal center positive for Bcl-6 and negative for Bcl-2 indicate?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Brief Answer: BCL There genes are expressed in Non Hodgkin Lemphoma They have significant in prognosis and therapy of the disease Hope I have answered your query. Let me know if I can assist you further.