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What Do The Following Lab Test Result Indicate?

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Posted on Thu, 8 Oct 2015
Question: Hi. I just for my annual lab results and had 3 abnormal results. They were 1)Absolute Monocytes 182 cells/uL. 10 months ago labs it was 403. 2)Bun/Creatinine Ratio 31(calc) 3)Creatinine 0.49 mg/dL. 10 months ago labs it was 55.
All other results reported were within range the report says. I've never had any abnormal results before so was just curious what these abnormal could indicate. I am a female -59 yrs old. Thank you.
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Answered by Dr. Michelle Gibson James (52 minutes later)
Brief Answer:
low creatinine normally caused by decrease in muscle mass

Detailed Answer:
Hi, thanks for using healthcare magic

(1) monocytes are a type of white blood cell ( the WBC) and are not interpreted on their own meaning that the WBC value has to be looked at as well to see if this is in the normal range

The breakdown under the WBC is to say how many of the different types of white blood cells are present.

Your present monocytes are below the normal range. A decrease in monocytes is called monocytopenia.
This can be due to less serious causes such as stress or more serious causes such as types of leukemia.
In some persons may be due to infections.

Leukemia would cause other changes in the white cell count so if these are normal then it is not likely at all.

Since it is previously normal and the other parts of the white cell is normal then your doctor may choose to repeat and monitor.

(2)bun/creat ratio is increased because the creatinine has decreased as compared to the bun

The decrease in the creatinine means that when it divides into the bun,the ratio would be higher.

A decrease in creatinine usually do not indicate any problems, it is more commonly due to a low muscle mass.

Summary: (1) if the over white cell count is normal then it is unlikely the decrease in monocytes on its own is significant
Your doctor may monitor

(2)low muscle mass is the main cause of a decrease in creatinine, the decrease in creatinine would cause the ratio to increase

I hope this helps,feel free to ask any other questions
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16808 Questions

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What Do The Following Lab Test Result Indicate?

Brief Answer: low creatinine normally caused by decrease in muscle mass Detailed Answer: Hi, thanks for using healthcare magic (1) monocytes are a type of white blood cell ( the WBC) and are not interpreted on their own meaning that the WBC value has to be looked at as well to see if this is in the normal range The breakdown under the WBC is to say how many of the different types of white blood cells are present. Your present monocytes are below the normal range. A decrease in monocytes is called monocytopenia. This can be due to less serious causes such as stress or more serious causes such as types of leukemia. In some persons may be due to infections. Leukemia would cause other changes in the white cell count so if these are normal then it is not likely at all. Since it is previously normal and the other parts of the white cell is normal then your doctor may choose to repeat and monitor. (2)bun/creat ratio is increased because the creatinine has decreased as compared to the bun The decrease in the creatinine means that when it divides into the bun,the ratio would be higher. A decrease in creatinine usually do not indicate any problems, it is more commonly due to a low muscle mass. Summary: (1) if the over white cell count is normal then it is unlikely the decrease in monocytes on its own is significant Your doctor may monitor (2)low muscle mass is the main cause of a decrease in creatinine, the decrease in creatinine would cause the ratio to increase I hope this helps,feel free to ask any other questions