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What do moderate involutional changes in the parenchyma of the brain suggest?

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Posted on Tue, 24 Jul 2018
Question: My dad had a brain MRI done to rule out dementia. He has significant short term memory issues and has gone from being a pretty nice man to cantankerous and difficult over the last 5 yrs or so.

The MRI indicates that he has “moderate involutional changes of the brain parenchyma”. Does this support a diagnosis of dementia or is it normal brain atrophy of an elderly person?
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Answered by Dr. Erion Spaho (42 minutes later)
Brief Answer:
Involutional changes don't mean necessary dementia.

Detailed Answer:
Hello and thanks for using HCM.

I have read your question and understand your concerns.

Mild to moderate involutional changes may be seen in elderly people, they don't mean necessary dementia.

Dementia is a diagnosis achieved mainly clinically.

Neuropsychological tests are necessary to evaluate the current cognitive function.

Discuss with your father's Neurologist about these issues.

Hope you found the answer helpful.

Let me know if I can assist you further.

Greetings.
Above answer was peer-reviewed by : Dr. Yogesh D
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Dr. Erion Spaho

Neurologist, Surgical

Practicing since :2004

Answered : 4256 Questions

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What do moderate involutional changes in the parenchyma of the brain suggest?

Brief Answer: Involutional changes don't mean necessary dementia. Detailed Answer: Hello and thanks for using HCM. I have read your question and understand your concerns. Mild to moderate involutional changes may be seen in elderly people, they don't mean necessary dementia. Dementia is a diagnosis achieved mainly clinically. Neuropsychological tests are necessary to evaluate the current cognitive function. Discuss with your father's Neurologist about these issues. Hope you found the answer helpful. Let me know if I can assist you further. Greetings.