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What Causes Weight Gain And Heat Intolerance While On Synthroid, Prednisone And Levothyroxine?

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Posted on Tue, 5 Jul 2016
Question: I have hypothyroidism. I take 175 MCG of Synthroid daily along with 2.5 or 5mg of PreniSone daily.
I am an active 72 year old and walk 2.5 to 3 miles a day. Two things have happened lately, I have become heat intolerant and gained a few pounds. Can you help?
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Answered by Dr. Mirjeta Guni (2 hours later)
Brief Answer:
Hello!

Detailed Answer:
Hello and thank you for asking!
I read your query and understood your concern!
175 mcg of levothyroxine is a high dose and should be monitored every 6 months if the last hormonal level has been within the normal ranges.
Heat intolerance is a symptom of over dose of levothyroxine, anyway it should be confirmed laboratorically.
The over weight might is a side effect of the prednisone treatment.
So i would recommend you to check the TSH level and to adjust the dose of levothyroxine if abnormal.
Hope thw information will help and i am opened for further questions.
Kind regards,
Dr.Mirjeta
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.
Above answer was peer-reviewed by : Dr. Naveen Kumar
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Answered by
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Dr. Mirjeta Guni

Endocrinologist

Practicing since :2006

Answered : 2414 Questions

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What Causes Weight Gain And Heat Intolerance While On Synthroid, Prednisone And Levothyroxine?

Brief Answer: Hello! Detailed Answer: Hello and thank you for asking! I read your query and understood your concern! 175 mcg of levothyroxine is a high dose and should be monitored every 6 months if the last hormonal level has been within the normal ranges. Heat intolerance is a symptom of over dose of levothyroxine, anyway it should be confirmed laboratorically. The over weight might is a side effect of the prednisone treatment. So i would recommend you to check the TSH level and to adjust the dose of levothyroxine if abnormal. Hope thw information will help and i am opened for further questions. Kind regards, Dr.Mirjeta