Question: Hello, I'm concerned about my daughter. She's 19, and has been complaining of tiredness, she's had bouts of nausea, soreness in the throat area some night sweats and a slight loss of appetite. This all started about 5/6 months ago. They found nodules on her thyroid. One came back benign and one was inconclusive even with FNA. We initially thought that it was low thyroid level, so we started her on synthroid. It seemed to help her at first but now not so much. We are beginning to wonder what else could be wrong because the symptoms seem to be getting worse. We have been to an ENT twice about her throat soreness but he seems to keep writing it off as nothing. All of her blood test have came back normal, but we don't know if they are checking for the right things. We do know something is very wrong and we are very concerned. What other possible things could this be a sign of? Please help.

Thank you for your response. No weight loss but interestingly there has been a slight decrease in appetite. And today, she ran a low grade fever. Im not sure what you mean by predisposition for pathology. Can you explain more on that? I do not have any exams to attach as we did not get a copy of the lab reports. Menstrual cycle is regular. This is all just really concerning as we went online and looked up lymphoma, both hodgkins and non hodgkins, and she has most of the symptoms so as parents naturally we are freaking out. We will not be able to get back to see her doctor until next week.

Thank you Doctor. All i know is that her symtoms seem to be getting worse. She was diagnosed with thyroid nodules about 6 months ago. The endo seems to think they are not cancerous. He also think she does not need to be on synthroid mainly due the lab results. At first it seemed to help but not so much now. She has went from .25 to .50 on dosage. Now its like its not even working. The soreness around the throat and neck area were diagnosed by her ENT as TMJ. He did feel her neck and throat and did not notice anything except the nodule. No swollen lymph nodes or anything. But, during all of this she was having bouts of nausea and some night sweats. This was something she had not told me. Now the fatigue seems to be getting worse. If her symtoms are not suggestive of lymphoma, do you think some of the symtoms could be caused by too much synthroid? And what about her neck and throat soreness? Im starting to think now since we have has two doctors tell us that she does not need to be on synthroid, mainly due to her labs, coupled with the fact that its no longer working, that the synthroid may be doing more harm than good. I just dont know what to do or think. I wish we could take her in today for labs. Im glad to know you think this is not suggestive of lymphoma, but, what else could it be?

Thank you Dr. Mirjeta

Thanks. I do nont have any pic of her neck/throat. Theres really nothing visible. She just complains of soreness and tenderness. While at work today she ran a fever and srarted to sweat again. This is a place where they keep it 61 degrees. The bout did not last very long she said. I think she also mentioned a touch of nausea. Do you think we should go straight to the Endo or take her to her PCP first?

The bouts of nasusea and sweating have been happening for about a month or two. Not sure about the fever. These symtoms mostly started around the time she started taking the synthroid. The fatigue and throat/neck soreness were present before starting the synthroid. Since they have done CT scans and sonagrams of her throat and have not found anything but the nodules, it is possible that these nodules are causing her throat discomfor? Also, is it possible that her symptoms are just side effects of the synthroid?