Thanks for writing to us with your health concern.
With 5 negative HPTs, you are not pregnant.
That is for sure.
You might be testing too soon - cannot really comment as you have not mentioned any dates.
The symptoms of tiredness
and sore breasts could be indicative of an approaching period.
Otherwise, do take a blood B HCG test to be absolutely sure, in conjunction with a pelvic ultrasound
With age, what changes is that there could be other reasons for the spotting followed by irregular missed periods - stress, weight gain, medications, late nights, travelling, hypothyroidism
, endometrial hyperplasia
, setting in of perimenopause, etc.
If you are going in for a formal evaluation, please have the hormones measured also - FSH, LH , TSH, Prolactin
All the best.
Please feel free to discuss further.