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    What causes stiffness and burning sensation in lower legs while on Synthroid?

Posted on Wed, 1 Jun 2016 in Thyroid Problem and Hormonal Problems
Question: I began in taking synthroid in XXXXXXX 2015, by August I was having extreme stiffness and burning sensations in my lower legs , top of feet and ankles. The stiffness is worse following walking.when it is really bad I trip over my toes and drag my left leg. I work at a very physical job. I am wondering if the Synthroid is not tolerated well by my body. Started out with TSH 9.5 went down to 4. Last checked was up to 6.75 I have hashimotos. I am supplementing recently with Vit D,selenium, B12, and iron because it was below normal which is associated with synthroid use, and omega 3 . The supplementation has helped with general malaise, by improving energy and motivation. Would like some help with these symtoms associated with stiff burning tendons.
Answered by Dr. Shehzad Topiwala 46 minutes later
Brief Answer:
Hormone tests

Detailed Answer:
Sorry to learn about your bothersome symptoms.

A general goal for the TSH for someone on treatment is around 1 to 2.
Likewise, the optimal 25 hydroxy Vitamin D blood levels are 40 to 60 ng/ml.

So what I am implying here is that after correctly diagnosing an under-active thyroid condition and vitamin D deficiency, it is important to treat in order to achieve targets.
If these are not in the desirable range then muscle and tendon related pains can occur.

I strongly encourage you to consult an endocrinologist in-person to see where you stand with respect to these levels.

When I see someone like you in my practice, I typically order the following blood tests in addition to a detailed physical examination:

CBC (Complete Blood Count, also known as Hemogram; includes Hemoglobin, WBC and Platelet counts)
Electrolytes (Sodium and Potassium in particular)
HbA1c (Glycosylated Hemoglobin = your 3 month glucose average)
Liver function tests (SGOT , SGPT, Albumin, Bilirubin, Alkaline Phosphatase)
Kidney function tests (BUN, Creatinine)
Free T4
Anti Thyroid Peroxidase (TPO) antibodies
Anti Thyroglobulin antibodies
25 hydroxy Vitamin D

None of these tests require any fasting and can be done at any time of the day

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
Answered by
Dr. Shehzad Topiwala


Practicing since :2001

Answered : 1663 Questions


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