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What causes severe fatigue, weight loss, loss of appetite and intermittent fever?

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Posted on Mon, 25 Jul 2016
Question: My brother (26 years) has 85,000 wbc blood count. He feels very tired, became lean, not able to eat anything, intermittent fever. Doc said it could be CML? Type of blood cancer? is it curable? if it is cml he might be in which stage with this wbc count? what could be the life expectancy of the person isolated with this? pls suggest.
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Answered by Dr. Deepak Sundriyal (39 minutes later)
Brief Answer:
Hello dear. CML is a good type of cancer.

Detailed Answer:
Hello dear. I understand your concern for your brother.
Yes it could be CML. That can be ascertained by a peripheral smear examination, blood study for XXXXXXX chromosome and BCR -ABL translocation test.
Stage will be determined by a marrow and peripheral blood smear examination.
It has 3 stages- chronic phase, accelerated phase and blast phase. Most of the patients are diagnosed in chronic phase of disease. Chronic phase of the disease has good prognosis. They can be very well controlled on oral drug called tyrosine kinase inhibitors(imatinib, dasatinib etc).
Survival is also very good upto the tune of more than 10 years and sometimes even 15 years and more.
So no need to worry. Get him diagnosed and treated.
Thanks and regards

Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Deepak Sundriyal

Oncologist

Practicing since :2005

Answered : 1546 Questions

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What causes severe fatigue, weight loss, loss of appetite and intermittent fever?

Brief Answer: Hello dear. CML is a good type of cancer. Detailed Answer: Hello dear. I understand your concern for your brother. Yes it could be CML. That can be ascertained by a peripheral smear examination, blood study for XXXXXXX chromosome and BCR -ABL translocation test. Stage will be determined by a marrow and peripheral blood smear examination. It has 3 stages- chronic phase, accelerated phase and blast phase. Most of the patients are diagnosed in chronic phase of disease. Chronic phase of the disease has good prognosis. They can be very well controlled on oral drug called tyrosine kinase inhibitors(imatinib, dasatinib etc). Survival is also very good upto the tune of more than 10 years and sometimes even 15 years and more. So no need to worry. Get him diagnosed and treated. Thanks and regards