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What Causes Rise In HCG Levels In Pregnancy?

Posted on Mon, 7 Apr 2014

Question: Hi i m xxxxx , my lmp date was 13th or 14th feb ( not sure) i got my beta hcg test done on 13th march, it was 47 n today ie 15 march got my beta hcg test done agin it was 173 my serum progestrone level on 14th march was 22.28 i already had 2 miscariages in past ( one at 6 mnths n the other at 1 n 1/2 mnths , ) before trying third time i got all advance test done n they were negative , my cycle has always been normal, i m not able to understand why my levels are low n wht could i do to prevent any mishappening this time , please suggest ?

Answered by Dr. Sree Gouri SR (1 hour later)

Brief Answer: Beta HCG injections Detailed Answer: Hi, Thanks for the query. According to your history as your last menstrual period was 13th February, by March 15th it will be 31 days. According to that your beta HCG levels are within normal levels. Reference: http://americanpregnancy.org/duringpregnancy/hcglevels.html Your progesterone levels are also within normal limits. Reference:http://www.nlm.nih.gov/medlineplus/ency/article/003714.htm You repeat the beta HCG levels after 2 days. Depending on the result further management can be planned. As you are having previous two miscarriages, better to go for twice a week beta HCG injections till the completion of first trimester with your doctor's advice. Hope I have answered your query. I will be available to answer followup queries. If you are satisfied with the answer, please give your review at the end of the discussion. Take care.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Sree Gouri SR (25 hours later)

Hi doc I got my beta hcg done again on 18th march it was 217 only n my serum progestrone level was more than 60 , my dr got woried n got my tvs done to see if any kind of ectopic pregnancy or any embroyinc sac was present Acc to sonogrphy reports no sign of ectopic pregnancy was found , reports are not wth me so i cannot attach but acc to it my uterus is clear , large amt of fluids are present n no sign of clots seen , she was saying that my endometrium lining is irregular from some sides measuring 17mm in thickness , last time in nov 13 i had got my 3 d sono done it was perfectly normal Till now i never had a bleeding n didnt pass any clots , my dr advised me to go for beta hcg test again , Honestly i m just depressed , i know everything is shattered I wanted to tell you ANA ,hbA1c, IgM, IgG, anti-dsDNA , torch , IgG n genetic karyotyping n genetic chromosomal test done last sept -13 , they were all negative As told by doctor my problem is that my body dont produces less hcg when i m pregnant . Is there no t/ t before pregnancy that my body produces adequate harmones, my cycle is always regular Could u also suggest me any doctor who can help me n solve my problems , i live in mumbai Please do something for me

Answered by Dr. Sree Gouri SR (13 minutes later)

Brief Answer: Repeat ultrasound after one week Detailed Answer: Hi, Beta hcg levels suggesting the possibility of pregnancy. Though the levels are not doubling, increase is there. Ultrasound may not detect early pregnancy sometimes. That too as you are not sure of lmp, we cannot completely relay on ultrasound findings. Sometimes the only sign that can be seen in early weeks of pregnancy is thickening of endometrium. So, better to go for repeat ultrasound after one week. Meanwhile you can go for hcg injections with your doctor's advice. After one week depending on ultrasound findings and beta hcg levels you can come to one conclusion regarding pregnancy. Take care.

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar