Question: My son, who is 30, has ARPKD and had his first kidney transplant
at age 10, then another one at 24. Both living donors. Well, now, 6 and half years into his second transplant, his microalbumin
, urine and ratio are going up dramatically. His Microalbumin is 604 and the ratio is 1793.3. His CR is 2.55 and BUN is 57. However, his creatinine
clearance after a 24 hour urine is 63.81 mL/minute. So, his Nephrologist
is saying he's stable for now with the kidney function, BUT is unsure of what to do next. He has been talking about taking the chemotherapy
durg, Rituxin, but are worried about the immune suppression being even worse on this drug. He had a kidney biospy a year ago and it showed no rejection. Any ideas of what could be causing this huge jump in microalbumin? Also, he had been put on Losartan
a year ago and it did seem to control this, until just recently. Any advice would be appreciated. He and and his doctor live 7 hours away and I can't ask his doctor these detailed questions because of HIPPA rules, etc. Can somebody give me some guidance? A worried Dad.