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What Causes Phelmorphic Sarcoma Tumor In The Leg?

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Posted on Mon, 3 Feb 2014
Question: Please tell what could cause my daughter to get a phelmorphic Sarcoma Tumor in her leg - size of a football?Can Stress cause this type of cancer, or overuse of the tumor leg?
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Answered by Dr. Rohan Khandelwal (17 minutes later)
Brief Answer: Environmental & Genetic factors Detailed Answer: Dear Ma'am, Sorry to hear about your daughter's condition. Sarcomas can be of various types and there have been many risk factors implicated in the development of sarcomas. 1. Genetic mutations, which gradually add up, can lead to these lesions. Mutation in the p53 gene are quite common in these patients. 2. Smoking & Alcohol consumption can increase the risk of these cancers 3. Exposure to radiation These are some of the factors which can predispose to a sarcoma but it is very difficult to pinpoint one cause for your daughter's condition. She should be thoroughly investigated. MRI of the limb, Ct scan of the thorax and abdomen and a biopsy of the lesion. This should be followed by excision of the lesion and chemotherapy. Hoping for the best. Please feel free to clarify any other query.
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Rohan Khandelwal

Oncologist, Surgical

Practicing since :2008

Answered : 576 Questions

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What Causes Phelmorphic Sarcoma Tumor In The Leg?

Brief Answer: Environmental & Genetic factors Detailed Answer: Dear Ma'am, Sorry to hear about your daughter's condition. Sarcomas can be of various types and there have been many risk factors implicated in the development of sarcomas. 1. Genetic mutations, which gradually add up, can lead to these lesions. Mutation in the p53 gene are quite common in these patients. 2. Smoking & Alcohol consumption can increase the risk of these cancers 3. Exposure to radiation These are some of the factors which can predispose to a sarcoma but it is very difficult to pinpoint one cause for your daughter's condition. She should be thoroughly investigated. MRI of the limb, Ct scan of the thorax and abdomen and a biopsy of the lesion. This should be followed by excision of the lesion and chemotherapy. Hoping for the best. Please feel free to clarify any other query.