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What causes neonatal seizures?

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Posted on Tue, 8 Dec 2015
Question: Hi, My baby boy is of 1 month. He was seizure at the age of 8 month 3 weeks and weight was 1.76 kg. Last usg report of his mother shows fatal left kidney is mild hydronefrotic, two vessel umbilical cord (single artery). he had jaundice at the age of 5 day 16.26 mg/dl and at the age 7 day 17.44 mg/dl. After photo therapy recovered. Now the problem is at the age of 19 day he has a type of convulsion 3 times. We consult Doctor and start gardenal syrup, Macalvet Syrup, total 10 doses of Orzid injection 250 mg 1/3 for infection and evion syrup.. After 7 days we stop Gardenal and find the attack at the very next day... What to do for above all the problem?? Please show me the right way if possible with little explanation... My family and me worrying too much.

Thanks in advance..


Regards
XXXX
doctor
Answered by Dr. Neeraj Kumar (34 minutes later)
Brief Answer:
Requires investigations and continuation of phenobarbitone

Detailed Answer:
Hello XXXX,
I have gone through your question and understand your concerns.
This is a hard time for a family to celebrate the birth of a baby and to deal with medical issue.
Neonatal seizures are due to many causes and in around 50% resolves without having any significant impact on future development.
In your baby the cause may be low birth weight, raised bilirubin or some infection (less likely).
In view of preterm, fetal left kidney with hydronephrosis and single umbilical artery it is required to get evaluated for chromosomal abnormalities and genetic syndrome.
His karyotying, MRI brain, EEG and USG of baby to be done for complete evaluation.
Further blood workup should be planned according to reports.
The phenobarbitone should be continued. In asymptomatic cases it can be stopped after 3 months.
Consultation with a paediatric neurologist will help you follow right path.
Prognosis also depends upon investigations and treatment response.
Hope you found the answer helpful.
Do get back with further queries.
Regards
Dr Neeraj Kumar
Neurologist

Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
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Answered by
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Dr. Neeraj Kumar

Neurologist

Practicing since :2006

Answered : 2263 Questions

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What causes neonatal seizures?

Brief Answer: Requires investigations and continuation of phenobarbitone Detailed Answer: Hello XXXX, I have gone through your question and understand your concerns. This is a hard time for a family to celebrate the birth of a baby and to deal with medical issue. Neonatal seizures are due to many causes and in around 50% resolves without having any significant impact on future development. In your baby the cause may be low birth weight, raised bilirubin or some infection (less likely). In view of preterm, fetal left kidney with hydronephrosis and single umbilical artery it is required to get evaluated for chromosomal abnormalities and genetic syndrome. His karyotying, MRI brain, EEG and USG of baby to be done for complete evaluation. Further blood workup should be planned according to reports. The phenobarbitone should be continued. In asymptomatic cases it can be stopped after 3 months. Consultation with a paediatric neurologist will help you follow right path. Prognosis also depends upon investigations and treatment response. Hope you found the answer helpful. Do get back with further queries. Regards Dr Neeraj Kumar Neurologist