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What Causes Neausea,dry Heaves And Migraine When On Medication For Depression?

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Posted on Mon, 10 Feb 2014
Question: I have had moderate depression most of my adult life and finally found that wellbutrin generic with Cymbalta brand had a lasting and positive effect on my depression. Now there is a generic for Cymbalta and of course insurance insists that is what I take. After 3 days of the generic, I am nauseous, having dry heaves, and a migraine. Related or just a coincidence?
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Answered by Dr. Srikanth Reddy (1 hour later)
Brief Answer: Clarification Detailed Answer: Hello, Thanks for using health care magic for posting your query. I have gone through your question in detail and I can understand what you are going through. However I would require a couple of more details to help you in answering your query in a better justified way. 1. Is it the same dosage of duloxetine? 2. Any previous history of migraine? 3. Any fever? Hope to hear from you at your earliest convenience. Regards and wish you good health, Dr. Srikanth Reddy MD Neuro-Psychiatrist and Sexologist
Above answer was peer-reviewed by : Dr. Shanthi.E
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Follow up: Dr. Srikanth Reddy (35 hours later)
Thank you for your response! 1. The dosage is identical - 90 mg/ day of cymbalta and now 90 mg/day of duloxitine 2. until about 5 years ago migraines occurred almost bi weekly. Now I rarely have them- maybe 3 times per year. 3. There has been no fever. At this time the nausea and loose stool continue. I'm eating small amounts of eggs and chicken soup. Lots of saltine crackers and sprite or sometimes coca cola.
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Answered by Dr. Srikanth Reddy (17 hours later)
Brief Answer: Unlikely due to Duloxetine Detailed Answer: Hello Thanks for the follow up information. It seems your physical illness is simply coinciding with the drug change over. If the dosage is same then the mere change over to the generic drug from the brand drug will not cause any problem. Both generic drugs and brand drugs are supposed to have the same amount of drug as per the FDA. It seems you are having a flue like illness and it will settle down on its own. Keep yourself properly hydrated and drink plenty of fruit juices preferably coconut water. Cocacola should not be a good option. Instead of crackers take plenty of salads which will provide roughage. Regarding migraine, you may take painkillers or sumatriptan initially but later on prefer going for divalproex for prophylaxis. Hope I am able to answer your concerns. If you have any further query, I would be glad to help you. If not, you may close the discussion and if possible you may rate the answer for me, so that I get a good feedback. In future if you wish to contact me directly, you can use the below mentioned link: bit.ly/dr-srikanth-reddy Wish you good health, Kind regards Dr. Srikanth Reddy M.D.
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Shanthi.E
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Dr. Srikanth Reddy

Psychiatrist

Practicing since :2007

Answered : 2770 Questions

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What Causes Neausea,dry Heaves And Migraine When On Medication For Depression?

Brief Answer: Clarification Detailed Answer: Hello, Thanks for using health care magic for posting your query. I have gone through your question in detail and I can understand what you are going through. However I would require a couple of more details to help you in answering your query in a better justified way. 1. Is it the same dosage of duloxetine? 2. Any previous history of migraine? 3. Any fever? Hope to hear from you at your earliest convenience. Regards and wish you good health, Dr. Srikanth Reddy MD Neuro-Psychiatrist and Sexologist