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What Causes Mildly Elevated Globulin Levels?
Question: High globulin level at 4.0 a/g ratio 1.1 and albumin is 4.3 what does this mean
Brief Answer:
A:G ratio is normal but globulin mildly elevated
Detailed Answer:
Hello,
Welcome and thanks for your query.
The blood protein consists of Albumin which is made in the liver and globulin which is increased in certain diseases and conditions.
The albumin level in the blood is normal. Albumin Globulin ratio is normally more than 1. When globulin level is elevated infections, chronic inflammatory conditions and certain malignancies should be investigated for.
Take care
A:G ratio is normal but globulin mildly elevated
Detailed Answer:
Hello,
Welcome and thanks for your query.
The blood protein consists of Albumin which is made in the liver and globulin which is increased in certain diseases and conditions.
The albumin level in the blood is normal. Albumin Globulin ratio is normally more than 1. When globulin level is elevated infections, chronic inflammatory conditions and certain malignancies should be investigated for.
Take care
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
What tests should be done? Normal CBC can I send my full results to you how would I do that I am nervous about cancer
I have attached my report for you to view
I have attached my report for you to view
Brief Answer:
A large number of conditions can cause
Detailed Answer:
Hello XXXXXXX
Sorry for the delay in getting back to you.
We live in different time zones and hence the delay.
The result you uploaded as far as I can make out has only HDL/LDL ratio, ALT and Osmolality.
ALT is a liver enzyme and is normal. Since the Albumin and ALT are normal, it is unlikely that a liver disease is the cause of the relatively high globulin.
The commonest cause of Globulin elevation are infections, liver diseases, blood diseases like leukemias ( this is unlikely with normal CBC), auto immune diseases , certain malignancies like Lymphoma, cancer of kidney, colon, prostate & biliary tree and multiple myeloma.
Do you have any symptoms or you discovered this on a routine examination?
If on a routine examination, I don't think you should worry too much. You could do Serum globulin electrophoresis to see which type of Globulin is elevated, an ESR , CRP and an abdominal ultrasonogram for screening.
Wish you a good day and good health
Dr Noble Zachariah
A large number of conditions can cause
Detailed Answer:
Hello XXXXXXX
Sorry for the delay in getting back to you.
We live in different time zones and hence the delay.
The result you uploaded as far as I can make out has only HDL/LDL ratio, ALT and Osmolality.
ALT is a liver enzyme and is normal. Since the Albumin and ALT are normal, it is unlikely that a liver disease is the cause of the relatively high globulin.
The commonest cause of Globulin elevation are infections, liver diseases, blood diseases like leukemias ( this is unlikely with normal CBC), auto immune diseases , certain malignancies like Lymphoma, cancer of kidney, colon, prostate & biliary tree and multiple myeloma.
Do you have any symptoms or you discovered this on a routine examination?
If on a routine examination, I don't think you should worry too much. You could do Serum globulin electrophoresis to see which type of Globulin is elevated, an ESR , CRP and an abdominal ultrasonogram for screening.
Wish you a good day and good health
Dr Noble Zachariah
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Sorry about that I just uploaded the other two pages of the report that are more useful. I am going to schedule an appointment with primary care tomorrow. I have no symptoms this was just done for routine physical. CBC is normal and rest of CMP was normal.
I should request serum globulin electrophoresis, esr, crp, and abdominal ultrasound? Is there possibility that this is just a minor variation with no medical significance? Thank you very much for time and reply.
Also would being only 24 make chance of cancer low such as prostate and colon. I exercise regularly and am generally active.
I should request serum globulin electrophoresis, esr, crp, and abdominal ultrasound? Is there possibility that this is just a minor variation with no medical significance? Thank you very much for time and reply.
Also would being only 24 make chance of cancer low such as prostate and colon. I exercise regularly and am generally active.
Brief Answer:
Malignancy is very unlikely.
Detailed Answer:
Your tests are normal except for the lipids.
I do not think that there is any thing serious and the chances of any malignancy in you is extremely low. I just mentioned them for completion and those tests may be done to reassure yourself.
You may also repeat the globulin level after a few months.
Malignancy is very unlikely.
Detailed Answer:
Your tests are normal except for the lipids.
I do not think that there is any thing serious and the chances of any malignancy in you is extremely low. I just mentioned them for completion and those tests may be done to reassure yourself.
You may also repeat the globulin level after a few months.
Note: For further follow up on related General & Family Physician Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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