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What Causes Low Hemoglobin Count, Weight Loss And Night Sweats?
Question: I have been feeling unwell for some months and my blood work is a bit off , transferrin saturation is 45, haemagkobin dropped from 13.8 to 10.7 in four weekS, platelets are normal , but I have very unusual bruising on my legs , I'm awaiting haematology consult , but I'd like to know what to expect and whst are the possible causes ! I have weight loss , exhaustion , night sweats ! My gp says it's not iron deficiency anaemia , and b12 and folate are normal too
Brief Answer:
Hi Can you upload your complete blood report here and photo of bruise
Detailed Answer:
Hi, I did review your concern mam.
Your drop in hemoglobin is significant.
Since your platelets are normal the bruising can be related to vessel problem or due problem in your coagulation or defect in patelet function.
With weight loss and night sweats these findings are worrisome for a bone marrow process.
It can range from a anemia due to any cause ( less likely iron deficiency anemia as transferrin sat is normal) like hemolysis or chronic myeloproliferative lesions like CML, myelofibrosis and so on. Also the marrow can be infiltrated by other cells like tuberculous infection or unwanted cells from other organs.
For a better picture, A bone marrow study is needed which I am sure you will be getting done with the hematology consult.
But if you can send the blood report with a morphological view of peripheral blood and also a photo of bruise I can analyse and may be give you more things that can be possible.
If you cannot upload it here you can send it to YYYY@YYYY with Sub: ATTN 'Dr Parth XXXXXXX Desai'
and I will get it soon.
I hope this helps.
Waiting for your reports.
Let me know if you have any more questions or concerns and also provide me feedback of your health.
Wish you all the best mam.
Sincerely,
Dr Parth Desai
Hi Can you upload your complete blood report here and photo of bruise
Detailed Answer:
Hi, I did review your concern mam.
Your drop in hemoglobin is significant.
Since your platelets are normal the bruising can be related to vessel problem or due problem in your coagulation or defect in patelet function.
With weight loss and night sweats these findings are worrisome for a bone marrow process.
It can range from a anemia due to any cause ( less likely iron deficiency anemia as transferrin sat is normal) like hemolysis or chronic myeloproliferative lesions like CML, myelofibrosis and so on. Also the marrow can be infiltrated by other cells like tuberculous infection or unwanted cells from other organs.
For a better picture, A bone marrow study is needed which I am sure you will be getting done with the hematology consult.
But if you can send the blood report with a morphological view of peripheral blood and also a photo of bruise I can analyse and may be give you more things that can be possible.
If you cannot upload it here you can send it to YYYY@YYYY with Sub: ATTN 'Dr Parth XXXXXXX Desai'
and I will get it soon.
I hope this helps.
Waiting for your reports.
Let me know if you have any more questions or concerns and also provide me feedback of your health.
Wish you all the best mam.
Sincerely,
Dr Parth Desai
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now
Above answer was peer-reviewed by :
Dr. Vinay Bhardwaj
Answered by
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