What causes inflammation around cancer tissues?

default
Posted on Sat, 29 Aug 2015 in Cancer
Question: Academic question.
If there is inhibition of T cell activation in cancer how do you explain why there is often inflammation in the surrounding tissues, eg esophageal cancer.
doctor
Answered by Dr. Indranil Ghosh 1 hour later
Brief Answer:
There are many pathways going on

Detailed Answer:
Hi
Thanks for your query.

In tumor microenvironment there are many cells and pathways going on. On one hand there are Treg cells which inhibit immunity/inflammation. On another hand are proinflammatory cells and helper T cells. The balance determines the level of inflammation and prognosis.

In general, infiltrating tumor lymphocytes are dissociated with better prognosis in cancer.

Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Indranil Ghosh

Oncologist

Practicing since :2004

Answered : 1495 Questions

premium_optimized

The User accepted the expert's answer

Share on
Question is related to
Medical Topics

Recent questions on  T cell

doctor1 MD

hi.......sir, i am 24yrs old and i got urine test, that i have pus cell 2-3/hpf,epithelial cells 2-4/hpf and others - yeast cells present. what r...

doctor1 MD

Hello these are skin lesions all over body could this be mycosis fungoides I am really terrified

doctor1 MD

How is the T cell involved in the destruction of auto immune in diabetes type 1 for children 7 years old. thank you very much doctor

doctor1 MD

Hi Sir plz suggest me that tuberculosis drug may extend the window period of hiv , if sum1 got tested for Elisa after 3 months, westernblot after...

doctor1 MD

to my understanding cancer is a mutated cell that rapidly multiplies. theoretically, if various types of cancerous cells were introduced into a...

doctor1 MD

Hello Dr.Galamanga I am a 50yr old African woman living with HIV, I have been on ARVs since 2005 a recent ESR reading from the lab was given as...

Get personalised answers from verified doctor in minutes across 80+ specialties

140 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
backtotop2