Question: I'm on statins Lipitor I have an totally dry mouth at night a thirst I cannot quench frequent urination every 20-30 minutes I am hardly getting any sleep lost grip strength in my hands and muscle fatigue and joint pain I am on a high dose 80mg I am getting very frustrated as no one can give me a solution I stopped them 3 days agao and my mouth has normal saliva levels now and I have less pain but as I recently had a stroke from a ruptured brittle plaque and the aretery dissected I need protection but this drug is making me very sick. I also take thyroxine for low thyroid function Plavix and a blood pressure/vaso dilator as I have developed secondary Raynuads as a result of the drugs with thyroid issues I need an answer to the totally dry mouth and urination after I drink My blood tests all come back normal except for low transferrin so I have started a protein supplement. I am becoming exhausted form the sleepless nights drinking and urinating for 3/4 hours It does not happen in the daytime

Thankyou for your reply I will now try to arrange the tests you suggest. In recent blood tests there have been no markers that indicate diabetes and my tests showed normal fasting glucose improving from what it previously was last 3 results are 27/10/16 4.8 24/3/2016 5.0 11/5/2015 6.9
The marker that had changed significantly was Transferrin
27/10/16 1.77 Saturation 52
11/05/15 2.01 Saturation 49
The report stating may be due to acute and chronic inflammatory disease (negative acute phase reactant) What I read in your response seems to be what I am experiencing Is this TYPE2 diabetes ? What is diabetes insipidus? I have no history of diabetes or any family history of this My life changed after the stroke and all the medication I subsequently am taking. The surgeon wants me on statins as protection as I have a polyurethane patch repair in the artery and sometimes plaques can adhere to the unusual surface. My cholesterol levels at present are 27/20/2016 Total Chol. 3.2 HDL 1.2 LDL 1.8 Non HDL Chol 2.0 Triglyceride 0.5 LDL/HDL Ratio 1.5 CHOL/HDL Ratio 2.7 Described as acceptable as the LDL is below 2.0 Does this help with your opinion that this nighttime driving thirst, it doesn't happen during the day, and constant urinination as I am drinking so much at night is diabetes insisipdus

I stopped taking the statin Lipitor 80mg 6 days ago Within 48 hours I had normal saliva production and the frequent cycle of unquenchable thirst lessened after 72 hours or 3 days I had lost all joint pain and stiffness, was back to a very good saliva production and sleeping through the night only getting up once or twice to urinate.
I have my energy back again . The Doctor has prescribed Crestor 10mg now.I have two questions about changing to it. It recommends if and take a half 50mg once daily you have thyroid issues which I do I have hashimoto's thyroidosis and take a half 50mg once daily to tell your Doctor and also the reason the Vascular Surgeon wanted me on Atorvastatin was because he said the research showed it was the best statin as it softened the plaque. Is there any such research applying to Crestor or rovustatin? I need some answers before I return to the stations as I had such severe side effects. I thank you for your opinion but I think diabetes insipidus would surely not stop so quickly just from the removal of a drug. My stroke did go up the central brain stem and possibly could have caused damage to the pituitary gland but I have had a dramatic improvement and complete loss of symptoms just from stopping Lipitor and am feeling 100% better each day. I realize it is better to be on the protective station but it must be one my body can tolerate. During this time since I began all this medication one year ago I have at the age of 65 developed primary Raynauds phenomenon which I read also has a relationship with Hashimoto's thyroiditis when you are placed on beta blockers. I ask these questions as I am trying to find out the best course of treatment to minimize my risk against further stroke. The surgeon said there was minimal evidence of atherosclerosis in my arteries when he operated but as I had a smokers plaque from passive smoking (I have never been a smoker)but my parents were heavy smokers and I am allergic to contrast XXXXXXX so could not have my arteries examined to identify any other blockages, I am seeking advice on my treatment options as I have twice now had to stop statins because if the side effects. Really the dehydration and frequency stopped within 48 hours. Thankyou.

Thankyou so much for your prompt replies and insight. I live in an isolated Country town 2 hours from medical assistance and nothing after 5pm. The advice you gave me assisted me to work thorough my understanding. I was continually being told it was not the statin but my health has improved dramatically in the past 8 days since I stopped taking it, particularly the brand Lipitor and I feel a lot more energetic and am functioning normally. I still need to resolve moments of dizziness and low BP. Currently I drink a glass of water with electrolytes and drink additional water as I was tld to do in hospital and elevate my feet as they also told me to do, until I get it up from 100-105 /60-66 and HR to 50-65. It's mainly on hot days that I get the dizziness, when I am putting my head up and down for any reason. I've always had a low heart rate and been a really fit person all my life until I was hurt in a workplace accident, knocked over by 18yr old boys fighting at school, thrown backwards into a wall where a boy weighing about 130-140 kgs and 6 ft 5in tall landed with his shoulder with force into my neck, crushing it. Subsequently 30 hours later I had a stoke and it was discovered that he had ruptured a brittle plaque and the artery had dissected. I am very fortunate to be alive with no side effects as I did not get access to clot busting drugs and was found to have a large hemorrhage and had an acute stroke. I weigh around 65kgs now and follow a very strict diet. I, as I told you before have an auto immune condition Hashimotos thyroiditis and as a result of the medication I have had to take recently have developed primary Raynaud's phenomenon. Thus my blood medication treatment was changed to Twynsta 40/5mg telimisartan/amlodipine and my blood pressure had already been around the 120/130 over 60/79 as a result of losing weight, a good diet and 80mg of telimisartan. This new drug is to assist my circulation and help with the Raynaud's has brought on the dizziness. Is the does too high perhaps? I ask lots of questions as I am well educated and have been a researcher in many all my life. I am interested in maintaining my good health for as long as possible after this challenging event. I thank you for your excellent support. It has been very helpful and informative. We live in the country and the Specialist I see is a two hour drive away. He saved my life when I had seconds to live, but accessing him to discuss all these unusual symptoms is not always easy. I have a lot of allergies and many are to prescription drugs and the preservatives in them, so I was not surprised by your answer that reactions to statins are rare. I have some of the rarest allergies to other drugs and chemicals.