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What causes elevated alkaline phosphatase in blood?

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Posted on Tue, 19 May 2015
Question: My husband had underwent a routine checkup and his Gamma GT elements seems to be extremely high... It is 289 U/L. What does this mean? What are the next steps to be taken?
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Answered by Dr. Riyanka Chail (1 hour later)
Brief Answer:
Advisable to meet a Physician and a hepatologist

Detailed Answer:
Hi,
Thanks for writing in to us.

This is Dr.Riyanka and I am glad to be helping you with your query.

The gamma-glutamyl transferase (GGT) test is used to determine the cause of elevated alkaline phosphatase (ALP).It is used to help detect liver disease and bile duct obstructions.
Only ALP will be elevated in disease of the bone .

Both ALP and GGT are elevated in disease of the bile ducts and in some liver diseases.

Along with GGT even Alanine transaminase , Aspartate Aminotransferase, ALP, and bilirubin is usually done.
An increased GGT level indicates that a person's liver is damaged but not the cause of injury.Its levels are high in alcoholic hepatitis.

Does the patient have any signs or symptoms presently?

Also it is advisable to meet a Physician and a hepatologist regarding the reports.

Hope this answers your query. Don't worry .
Do write back if you have any further doubts.


Get well soon
Dr.Riyanka

Above answer was peer-reviewed by : Dr. Neel Kudchadkar
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Answered by
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Dr. Riyanka Chail

General & Family Physician

Practicing since :2009

Answered : 818 Questions

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What causes elevated alkaline phosphatase in blood?

Brief Answer: Advisable to meet a Physician and a hepatologist Detailed Answer: Hi, Thanks for writing in to us. This is Dr.Riyanka and I am glad to be helping you with your query. The gamma-glutamyl transferase (GGT) test is used to determine the cause of elevated alkaline phosphatase (ALP).It is used to help detect liver disease and bile duct obstructions. Only ALP will be elevated in disease of the bone . Both ALP and GGT are elevated in disease of the bile ducts and in some liver diseases. Along with GGT even Alanine transaminase , Aspartate Aminotransferase, ALP, and bilirubin is usually done. An increased GGT level indicates that a person's liver is damaged but not the cause of injury.Its levels are high in alcoholic hepatitis. Does the patient have any signs or symptoms presently? Also it is advisable to meet a Physician and a hepatologist regarding the reports. Hope this answers your query. Don't worry . Do write back if you have any further doubts. Get well soon Dr.Riyanka