Question: 36 year old female/Hashimoto's hypothyroidism since March 2001. Well controlled on synthroid. Normal pap test January 2014. Two healthy pregnancies/children... ages 14 and 10. In March 2014, I skipped a menstrual cycle. No symptoms, no discomfort, no PMS symptoms. I went to Dr. I was/am obese. At that time, I weighed 278 pounds. HPT negative. FSH run, but at unknown point in my cycle... in range as far she could tell. She believed weight was causing hormonal changes. Period returned--no more than 60 day cycle. I did diet/exercise/started phentermine, and I lost 40 pounds. Everything seemed to be going well. Now something else is happening. I have had sore breasts for 2 weeks. Nausea for 2 weeks. Heightened sense of smell for 2 weeks. Painless clenching (same areas that clench and release with orgasm)off et on for 1 week. Lower back/pelvic pressure for 2 days. Dizziness approx 2 weeks ago, but seems to have resolved after 2-3 days. Urinary frequency for 7-8 days. No cola colored urine. No urgency. No dysuria. Concentrated yellow urine. No foul odor. I do not know the first day of my last period. I generally get them at the beginning of the month. I do not generally have any symptoms other than sore/heavy breasts for 1 week and pelvic pressure 1-2 days prior to starting. Moderate flow for 2 days, then 3-4 days of spotting. Husband had vasectomy in 2006. He completed his specimen checks, and we were given the all clear. HPT negative. Hot flashes x 2 days. Left-sided sciatica yesterday only. Poochy belly/above waistline noticed 2-3 days ago-not normal for me. Pear-shaped body. No pain with intercourse. No issues with vaginal discharge. Clear. Still wet and slick, not watery like I generally observe 1-2 days prior to starting my period. Still obese at 237 pounds. No family history of PCOS. Menarche at14. 32 day cycles until on BCP at 17-20 y/o... then 28 as expected. When I was pregnant, I did not have any symptoms of PMS. I just stopped having periods. No discomfort at all or any symptoms I am experiencing right now. Again, vasectomyand negative HPT, although not sure when I should have started period, I doubt pregnancy as cause. Any thoughts? I feel like I am potentially having false-pregnancy? Perimenopausal at 36? I have been an RN for 12 years. I suspect a transvaginal sono would help... maybe CBC, CMP, LH, HGB A1C, FSH, HCG, INSULIN, TSH, T4, thyroid antibodies... even GTT...