Sign-in to Ask A Doctor - 24x7
OR
Sign in with Google
What Causes Diarrhea While On Mirtazapine And Pregabalin?
Question: I take 30mg Mirtazapine & 150mg pregabalin @ night and 75mg pregabalin in the morning for anxiety & depression management. I have been this regime for past 4 months & have diarrhoea every morning since taking it. I eat well & never had bowel problems prior to this. My question is: would the chronic diarrhoea be a result of the medication or something separate. Many thanks for your advice.
Brief Answer:
pregabalin can cause diarrhoea
Detailed Answer:
Hello XXXXXXX
Thanks for writing to us.
You mentioned that you have complaints of diarrhoea since you started medicines. Mirtazapine causes constipation commonly and pregabalin can cause diarrhoea.
You are taking total 225 mg of pregabalin which is high dose. Likely possibility is that pregabalin is responsible for diarrhoea. We can confirm the same by reducing/stopping pregabalin.
Even after stopping pregabalin problem continues we need to search for other cause.
Hope I have answered your query, I will be happy to help further.
Regards,
Dr.Chintan Solanki.
pregabalin can cause diarrhoea
Detailed Answer:
Hello XXXXXXX
Thanks for writing to us.
You mentioned that you have complaints of diarrhoea since you started medicines. Mirtazapine causes constipation commonly and pregabalin can cause diarrhoea.
You are taking total 225 mg of pregabalin which is high dose. Likely possibility is that pregabalin is responsible for diarrhoea. We can confirm the same by reducing/stopping pregabalin.
Even after stopping pregabalin problem continues we need to search for other cause.
Hope I have answered your query, I will be happy to help further.
Regards,
Dr.Chintan Solanki.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Many thanks for your answer. The psychiatrist I see said I could adjust/decrease the pregabalin if I needed to. The anxiety is well under control these days. Would you suggest me decreasing the night dose to 75mg or keeping it at 150mg & stopping the morning dose? Thanks for your advice.
Brief Answer:
I would recommend night dose reduction
Detailed Answer:
Hi,
Thanks for follow up.
If I were your treating doctor I would like to reduce night dose to 75 mg first. After 1 week I would like to stop 75 mg morning dose and keep only night 75 mg dose.
Feel free to discuss further.
I would recommend night dose reduction
Detailed Answer:
Hi,
Thanks for follow up.
If I were your treating doctor I would like to reduce night dose to 75 mg first. After 1 week I would like to stop 75 mg morning dose and keep only night 75 mg dose.
Feel free to discuss further.
Note: For further guidance on mental health, Click here.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
Get personalised answers from verified doctor in minutes across 80+ specialties
