Get your Health question answered in 3 easy steps

148 Doctors Online
Owl Image
Dr. Andrew Rynne

Family Physician

Exp 18 years

I will be looking into your question and guiding you through the process. Please write your question below.

What causes cough after having methotrexate?

Answered by
Owl Image
Dr. Karen Steinberg

Internal Medicine Specialist

Practicing since :1981

Answered : 824 Questions

I have RA taking Methroxate,, was told to take 2 folic acid pills every day, to prevent side effects to medicine,, doing good ---except coughing and nose running and bleeding better than it has been , but still get goughing spells could this be be from med I'm taking or folic acid?
Mon, 11 Aug 2014 in General Health
Answered by Dr. Karen Steinberg 28 minutes later
Brief Answer:
Could be from methotrexate

Detailed Answer:
Hi, thanks for using Healthcare Magic. Folic acid is a vitamin that is needed for the proper formation of blood cells. Methotrexate can interfere with it so supplements are recommended. Folic acid is not likely to be causing your cough.

Methotrexate can cause damage (fibrosis or scarring) to the lungs in some people. This needs to be evaluated promptly. Inform your doctor of your cough and get a workup initiated. This might consist of chest x-ray or other imaging studies of your lungs, and breathing tests. But don't stop taking the methotrexate until you talk to your doctor and get the workup. It could be something else causing the cough. If it is the methotrexate then it will be stopped and another medicine tried.

Get seen right away. The damage from methotrexate is progressive, so if it is this medicine causing the problem, you'll want to know right away so you can stop any further damage from occurring.

Hope this answers your query. If you have further questions, I would be happy to answer them.
Above answer was peer-reviewed by

The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions

Recent questions on Fibrosis

doctor1 MD

Good Day My son has been suffering for almost a year now with hyperinflation, shortness of breath when active and low saturation levels if not permanently on oxygen. He has some form of fibrosis of the lungs from previous infections. He has never had a proper diagnosis of what his condition is but it appears that he has some form of pulmonary dysplasia possibly asthma but he has never been well enough to make a proper diagnosis for asthma. He has very sensitive airways and the right middle lobe of his lung is partially collapsed but we have been told that for the amount of lung that has collapsed, his hyperinflation and shortness of breath seems to be far to much. He is on bronchiole dialators, almost always on antibiotics because he seems to catch any infection very easily and is on permanent oxygen. He will be 3 in March. Is there anything that you can recommend I can do, or something you can suggest that maybe the doctors he has been seeing have maybe overseen, please I am desperate to get my son better. Kind Regards, Steve

doctor1 MD

I recently had some chest tightening and was seen in an ED. My CXR showed a small calcific density in the left upper lobe. I had a follow up CXR that showed a 2mm calcified granuloma and bilateral basilar atelectasis. My father has idiopathic pulmonary firbrosis. I have been referred to a pulmonologist, but was wondering if this could be fibrosis or some type of cancer. Thanks

doctor1 MD

I was diagnosed with intermittent testicular torsion 3 years ago and had orchiopexy performed with non absorbable sutures. Before the surgery my testicle would be backwards (180 degrees) 90% of the time or more and I had pain every day from it....

doctor1 MD

I am 39 yo. When I was pregnant with my second child (age 37) I was extremely SOB. I had PFT s done and they noted a low DLCO...about 50% predicted. All my other volumes tests were within normal limits. Since then I ve repeated the tests and the highest I ve gotten is 62%. I have no medical issues. I know a low DLCO can be assoc with anemia, pHTN, PE, pulm fibrosis ,etc. I have none of those issues either. What else is assoc with it and could it be a precursor to an issue I may develop? This may be off base as well, but is there a link with Mult Sclerosis?

doctor1 MD

Hi, may I answer your health queries right now ? Please type your query here...hello recently i was in the hospital and on the med papers i got on release said i have ( small bands of atelectasis versus fibrosis in the lower left lung base. can you tell me what that is please?

doctor1 MD

Was recently diagnosed with copd . Never smoked but grew up heavy secondhand smoke from parents. Waiting for results from ct to rule out a tumor or pulm fibrosis acc to pulmonologist. This morning i walked into a restaurant stood in line...

doctor1 MD

I have had a hemorrhoid for at least 10 years. It does not itch nor does it hurt. I have trouble getting everything out because it snakes out. When it is lower down it keeps my anus open and I don't feel it when I use the bathroom. What can I do?