What causes abdominal pain in a patient with IBS?

Posted on Wed, 13 May 2015

Question: I have been having Abdominal pain for last 10 months (it started after an episode of food poisoning). I was diagnosed with IBS. Have been taking MacRobonic (Rabeprazole sustained release) since I also have GERD (with mild symptoms) for last 3 months (1 capsule daily).
Recently, one of my doctors suggested he suspects there might be IBD also for which he prescribed Fecal Calprotectin test. I had the test done and the results are quite high 135 (mg/kg) when it should be less than 50 mg/kg. I happened to read the using PPI like Rabeprazole increases the values of Calprotentic test. I dont have any symptoms related to IBD like weight loss, bloody stools etc. Can you please suggest for how many days should I stop taking a PPI medicine before I can do a Fecal Calprotectin test?

Answered by Dr. Sagar (2 hours later)

Brief Answer:
At least 48 hours.

Detailed Answer:
HELLO
WELCOME TO HCM.
I appreciate your concern.
Yes, you know right.
PPI use can give high fecal calprotectin value.
Stop PPI atleast 48 hours before the test.
Hope it is helpful.
Regards.

Above answer was peer-reviewed by : Dr. Shanthi.E

Follow up: Dr. Sagar (23 minutes later)

Can you suggest some other tests which I can take up or discuss with my doctor to confirm if the problem is IBS or IBD ? Is colonoscopy a good way to determine with certainty if I am having IBD ?

Answered by Dr. Sagar (3 hours later)

Brief Answer:
Yes colonoscopy is a very sensitive procedure.

Detailed Answer:
Hello.
colonoscopy is the best test here.
But as it is invasive procedure calprotectin is done..
You can go for colonoscopy after discussing your doctor..
Hope this is helpful.
Regards.

Above answer was peer-reviewed by : Dr. Pradeep Vitta