HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

What Causes Gilbert's Syndrome?

default
Posted on Mon, 18 May 2015
Question: Hello. An elevated b12 of 1093 and bilirubin is 1.3. Should i be concerned
doctor
Answered by Dr. Panagiotis Zografakis (27 minutes later)
Brief Answer:
Not necessarily

Detailed Answer:
Hello,

slightly elevated bilirubin is unlikely to be a reason for concern. Most of the times it can be attributed to Gilbert's syndrome (which is a benign condition) or a chronic hemolytic anemia (like the hereditary types - thalassemia trait etc). Elevated vitamin B12 can be caused by various conditions like leukemia, chronic obstructive pulmonary disease, renal failure, diabetes, liver disease, obesity, polycythemia vera, congestive heart failure, etc

Exogenous B12 administration is another common cause.

I hope I've helped!
Contact me again, if you'd like more information.

Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Panagiotis Zografakis (5 minutes later)
Should i follow up with a specialist. My pcp didnt say anything. All my other levels were with in normal range
doctor
Answered by Dr. Panagiotis Zografakis (4 minutes later)
Brief Answer:
If everything else is normal then you can't do anything more

Detailed Answer:
Hi,

abnormal findings need to be adequately interpreted. For example, if you don't have signs (laboratory or clinical) of any liver disease then benign explanations for your bilirubin can be safely adopted.

Regarding B12, if you don't have any clinical examination findings (like an enlarged spleen or swollen lymph nodes) and no other laboratory findings then you can't do anything more. Your doctor should consider potential causes and give a proper explanation.

If nothing can be found, then this is all you can do.

Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Panagiotis Zografakis (21 minutes later)
I have had a lot of gastro problems and always tired. I made an appt. with my gastro. My pcp didnt ask me much. I think its time to find a new pcp
doctor
Answered by Dr. Panagiotis Zografakis (4 minutes later)
Brief Answer:
I can't advise you about that

Detailed Answer:
I can't criticize your PCP... gastrointestinal problems and tiredness is not a specific description, so I can't comment on that either.
If you'd like to provide a more detailed list of your problems then perhaps I could find a connection with the laboratory findings. Upload the full report would help me even more.

Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Panagiotis Zografakis (22 minutes later)
Pain in my lower back. I have had kidbey stones in the past. Ibs symtoms. Fatigued and dark circles under eyes and pale skin
doctor
Answered by Dr. Panagiotis Zografakis (4 minutes later)
Brief Answer:
No obvious connection with elevated B12

Detailed Answer:
I can't find any obvious link with the B12 result, particularly if the rest of the lab tests were normal. Clinical examination could reveal clues though, like the ones I mentioned in previous answers. Depending on clinical examination data, other tests could be employed like ultrasound scans or computed tomography to detect internal organ abnormalities.

Kind Regards!
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3809 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
What Causes Gilbert's Syndrome?

Brief Answer: Not necessarily Detailed Answer: Hello, slightly elevated bilirubin is unlikely to be a reason for concern. Most of the times it can be attributed to Gilbert's syndrome (which is a benign condition) or a chronic hemolytic anemia (like the hereditary types - thalassemia trait etc). Elevated vitamin B12 can be caused by various conditions like leukemia, chronic obstructive pulmonary disease, renal failure, diabetes, liver disease, obesity, polycythemia vera, congestive heart failure, etc Exogenous B12 administration is another common cause. I hope I've helped! Contact me again, if you'd like more information. Kind Regards!