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What Are The Side Effects Of Taking Melatonin?

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Posted on Tue, 7 Mar 2017
Question: A Doctor told a friend of mine that taking Melatonin make the brain to stop producing it. Is this true?
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Answered by Dr. Dariush Saghafi (1 hour later)
Brief Answer:
Oral intake has limited modulatory ability but CANNOT STOP production

Detailed Answer:
Thank you for your question. This question has actually been looked at in detail and you and your doctor may be happy to learn that the actual overall impact of dietary intake of melatonin whether in the form of foodstuffs or as straight up pills taken at bedtime for sleep purposes does not have nearly as great an impact on levels that are circulating in your bloodstream at nighttime compared to some impact during the day. Also, the impact of LIGHT on the production or not of melatonin is far more important and intense than the ingestion of dietary sources or supplements.

In conclusion, DARKNESS is the strongest environmental influence on the production of melatonin in the body is orders of magnitude greater than what is produced based upon dietary ingestion. Studies have demonstrated some minor influences on total melatonin production by ingestion of either supplements or dietary sources, however, in no study has it ever been shown nor would it be expected based upon the physiological principles of its production that dietary ingestion by itself can initiate a feedback loop effect on signaling in the hypothalamus by the diurnal synchronization neuronal network or pineal production of melatonin in order to halt its synthesis and release into plasma.

If I've provided useful and helpful information to your questions could you do me a huge favor by CLOSING THE QUERY and be sure to include some fine words of feedback along with a 5 STAR rating? Again, many thanks for submitting your inquiry and please let me know how things turn out.

Do not forget to contact me in the future at: www.bit.ly/drdariushsaghafi for additional questions, comments, or concerns having to do with this topic or others.

This query has utilized a total of 20 minutes of professional time in research, review, and synthesis for the purpose of formulating a return statement.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dariush Saghafi

Neurologist

Practicing since :1988

Answered : 2473 Questions

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What Are The Side Effects Of Taking Melatonin?

Brief Answer: Oral intake has limited modulatory ability but CANNOT STOP production Detailed Answer: Thank you for your question. This question has actually been looked at in detail and you and your doctor may be happy to learn that the actual overall impact of dietary intake of melatonin whether in the form of foodstuffs or as straight up pills taken at bedtime for sleep purposes does not have nearly as great an impact on levels that are circulating in your bloodstream at nighttime compared to some impact during the day. Also, the impact of LIGHT on the production or not of melatonin is far more important and intense than the ingestion of dietary sources or supplements. In conclusion, DARKNESS is the strongest environmental influence on the production of melatonin in the body is orders of magnitude greater than what is produced based upon dietary ingestion. Studies have demonstrated some minor influences on total melatonin production by ingestion of either supplements or dietary sources, however, in no study has it ever been shown nor would it be expected based upon the physiological principles of its production that dietary ingestion by itself can initiate a feedback loop effect on signaling in the hypothalamus by the diurnal synchronization neuronal network or pineal production of melatonin in order to halt its synthesis and release into plasma. If I've provided useful and helpful information to your questions could you do me a huge favor by CLOSING THE QUERY and be sure to include some fine words of feedback along with a 5 STAR rating? Again, many thanks for submitting your inquiry and please let me know how things turn out. Do not forget to contact me in the future at: www.bit.ly/drdariushsaghafi for additional questions, comments, or concerns having to do with this topic or others. This query has utilized a total of 20 minutes of professional time in research, review, and synthesis for the purpose of formulating a return statement.